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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3BGRL
All Species:
20.91
Human Site:
Y63
Identified Species:
41.82
UniProt:
O75368
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75368
NP_003013.1
114
12774
Y63
N
S
R
P
A
T
G
Y
P
L
P
P
Q
I
F
Chimpanzee
Pan troglodytes
XP_001145030
105
11772
E51
E
N
R
K
W
M
R
E
N
V
P
E
N
S
R
Rhesus Macaque
Macaca mulatta
XP_001101367
133
15151
Y82
N
S
R
P
A
T
G
Y
P
L
P
P
Q
I
F
Dog
Lupus familis
XP_549106
104
11762
Y53
N
N
R
P
A
T
G
Y
P
L
P
P
Q
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJU8
114
12793
Y63
D
S
R
P
S
T
G
Y
P
L
P
P
Q
I
F
Rat
Rattus norvegicus
XP_217566
114
12782
Y63
D
S
R
P
P
T
G
Y
P
L
P
P
Q
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519197
122
13752
N71
N
S
R
P
A
T
G
N
P
L
P
P
Q
I
F
Chicken
Gallus gallus
NP_001012592
114
12777
N63
D
R
R
P
A
S
G
N
P
L
P
P
R
L
F
Frog
Xenopus laevis
Q3KPU0
106
12454
P59
N
I
P
K
D
R
L
P
A
Q
G
N
P
L
P
Zebra Danio
Brachydanio rerio
Q6GMK7
105
12112
D55
W
M
Y
Q
K
I
P
D
E
K
R
P
E
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFP5
158
17470
H69
V
S
D
P
E
P
R
H
P
L
P
P
Q
L
F
Honey Bee
Apis mellifera
XP_624305
177
20052
Y62
S
I
A
R
E
S
K
Y
P
L
P
P
Q
I
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.1
80.4
85.9
N.A.
94.7
95.6
N.A.
78.6
86.8
55.2
53.5
N.A.
30.3
26.5
N.A.
N.A.
Protein Similarity:
100
92.1
82.7
87.7
N.A.
96.4
96.4
N.A.
87.6
94.7
71
69.3
N.A.
45.5
37.8
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
86.6
86.6
N.A.
93.3
60
6.6
6.6
N.A.
53.3
53.3
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
93.3
N.A.
93.3
86.6
13.3
13.3
N.A.
66.6
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
42
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
0
9
0
9
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
17
0
0
9
9
0
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% F
% Gly:
0
0
0
0
0
0
59
0
0
0
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
9
0
0
0
0
0
0
0
59
0
% I
% Lys:
0
0
0
17
9
0
9
0
0
9
0
0
0
9
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
75
0
0
0
25
0
% L
% Met:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
42
17
0
0
0
0
0
17
9
0
0
9
9
0
0
% N
% Pro:
0
0
9
67
9
9
9
9
75
0
84
84
9
0
9
% P
% Gln:
0
0
0
9
0
0
0
0
0
9
0
0
67
0
0
% Q
% Arg:
0
9
67
9
0
9
17
0
0
0
9
0
9
0
9
% R
% Ser:
9
50
0
0
9
17
0
0
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _