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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAMP4 All Species: 22.73
Human Site: S17 Identified Species: 35.71
UniProt: O75379 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75379 NP_003753.2 141 16397 S17 N D D D V T G S V K S E R R N
Chimpanzee Pan troglodytes XP_514347 124 14309 T10 D N K F Q K R T V E L T Y R G
Rhesus Macaque Macaca mulatta Q9N0Y0 116 12644 A11 T A A T A P P A A P A G E G G
Dog Lupus familis XP_537195 141 16319 S17 N D D D V T G S V K S E R R N
Cat Felis silvestris
Mouse Mus musculus O70480 141 16334 S17 N D D D V T G S V K S E R R N
Rat Rattus norvegicus P63025 103 11462 A11 G V P S G S S A A T G S N R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515123 141 16444 S17 N D D D V T G S V K S E R R N
Chicken Gallus gallus XP_001233852 159 18204 S35 N D D E V T G S V K S E R R N
Frog Xenopus laevis P47193 114 12454 A10 A P A A G P P A A A P G D G A
Zebra Danio Brachydanio rerio NP_957029 68 7914
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18489 152 16693 F17 S G S N N N D F P I L P P P P
Honey Bee Apis mellifera XP_394684 145 16557 A17 S A E D I K T A A K D E K E L
Nematode Worm Caenorhab. elegans O02495 109 12007 S13 D A G A Q G G S Q G G P R P S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFP1 221 25302 A68 G L T V L C M A D E T A G R N
Baker's Yeast Sacchar. cerevisiae P33328 115 12939 Y10 S S V P Y D P Y V P P E E S N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.9 29 96.4 N.A. 97.1 29.7 N.A. 91.4 79.8 29.7 41.1 N.A. 22.3 31 27.6 N.A.
Protein Similarity: 100 56 49.6 97.8 N.A. 99.2 52.4 N.A. 97.8 85.5 48.2 46.8 N.A. 50 56.5 49.6 N.A.
P-Site Identity: 100 13.3 0 100 N.A. 100 6.6 N.A. 100 93.3 0 0 N.A. 0 20 20 N.A.
P-Site Similarity: 100 40 13.3 100 N.A. 100 20 N.A. 100 100 6.6 0 N.A. 13.3 53.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.6 28.3 N.A.
Protein Similarity: N.A. N.A. N.A. 39.8 53.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 14 14 7 0 0 34 27 7 7 7 0 0 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 34 34 34 0 7 7 0 7 0 7 0 7 0 0 % D
% Glu: 0 0 7 7 0 0 0 0 0 14 0 47 14 7 0 % E
% Phe: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 14 7 7 0 14 7 40 0 0 7 14 14 7 14 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % I
% Lys: 0 0 7 0 0 14 0 0 0 40 0 0 7 0 0 % K
% Leu: 0 7 0 0 7 0 0 0 0 0 14 0 0 0 7 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 34 7 0 7 7 7 0 0 0 0 0 0 7 0 47 % N
% Pro: 0 7 7 7 0 14 20 0 7 14 14 14 7 14 7 % P
% Gln: 0 0 0 0 14 0 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 0 0 0 40 54 7 % R
% Ser: 20 7 7 7 0 7 7 40 0 0 34 7 0 7 7 % S
% Thr: 7 0 7 7 0 34 7 7 0 7 7 7 0 0 0 % T
% Val: 0 7 7 7 34 0 0 0 47 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 7 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _