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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAMP4
All Species:
20.3
Human Site:
S20
Identified Species:
31.9
UniProt:
O75379
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75379
NP_003753.2
141
16397
S20
D
V
T
G
S
V
K
S
E
R
R
N
L
L
E
Chimpanzee
Pan troglodytes
XP_514347
124
14309
L13
F
Q
K
R
T
V
E
L
T
Y
R
G
I
R
Y
Rhesus Macaque
Macaca mulatta
Q9N0Y0
116
12644
A14
T
A
P
P
A
A
P
A
G
E
G
G
P
P
A
Dog
Lupus familis
XP_537195
141
16319
S20
D
V
T
G
S
V
K
S
E
R
R
N
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
O70480
141
16334
S20
D
V
T
G
S
V
K
S
E
R
R
N
L
L
E
Rat
Rattus norvegicus
P63025
103
11462
G14
S
G
S
S
A
A
T
G
S
N
R
R
L
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515123
141
16444
S20
D
V
T
G
S
V
K
S
E
R
R
N
L
L
E
Chicken
Gallus gallus
XP_001233852
159
18204
S38
E
V
T
G
S
V
K
S
E
R
R
N
L
L
E
Frog
Xenopus laevis
P47193
114
12454
P13
A
G
P
P
A
A
A
P
G
D
G
A
P
Q
G
Zebra Danio
Brachydanio rerio
NP_957029
68
7914
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18489
152
16693
L20
N
N
N
D
F
P
I
L
P
P
P
P
N
A
N
Honey Bee
Apis mellifera
XP_394684
145
16557
D20
D
I
K
T
A
A
K
D
E
K
E
L
L
L
E
Nematode Worm
Caenorhab. elegans
O02495
109
12007
G16
A
Q
G
G
S
Q
G
G
P
R
P
S
N
K
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFP1
221
25302
T71
V
L
C
M
A
D
E
T
A
G
R
N
I
P
F
Baker's Yeast
Sacchar. cerevisiae
P33328
115
12939
P13
P
Y
D
P
Y
V
P
P
E
E
S
N
S
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.9
29
96.4
N.A.
97.1
29.7
N.A.
91.4
79.8
29.7
41.1
N.A.
22.3
31
27.6
N.A.
Protein Similarity:
100
56
49.6
97.8
N.A.
99.2
52.4
N.A.
97.8
85.5
48.2
46.8
N.A.
50
56.5
49.6
N.A.
P-Site Identity:
100
13.3
0
100
N.A.
100
13.3
N.A.
100
93.3
0
0
N.A.
0
40
20
N.A.
P-Site Similarity:
100
33.3
13.3
100
N.A.
100
33.3
N.A.
100
100
6.6
0
N.A.
6.6
60
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
28.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
0
34
27
7
7
7
0
0
7
0
7
14
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
7
7
0
7
0
7
0
7
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
14
0
47
14
7
0
0
0
40
% E
% Phe:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
14
7
40
0
0
7
14
14
7
14
14
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
7
0
0
0
0
0
14
0
0
% I
% Lys:
0
0
14
0
0
0
40
0
0
7
0
0
0
7
0
% K
% Leu:
0
7
0
0
0
0
0
14
0
0
0
7
47
40
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
7
0
0
0
0
0
0
7
0
47
14
0
7
% N
% Pro:
7
0
14
20
0
7
14
14
14
7
14
7
14
14
0
% P
% Gln:
0
14
0
0
0
7
0
0
0
0
0
0
0
14
7
% Q
% Arg:
0
0
0
7
0
0
0
0
0
40
54
7
0
7
7
% R
% Ser:
7
0
7
7
40
0
0
34
7
0
7
7
7
0
0
% S
% Thr:
7
0
34
7
7
0
7
7
7
0
0
0
0
0
0
% T
% Val:
7
34
0
0
0
47
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
7
0
0
0
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _