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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX14 All Species: 25.76
Human Site: S249 Identified Species: 51.52
UniProt: O75381 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75381 NP_004556.1 377 41237 S249 Q I P V K S P S P S S P A A V
Chimpanzee Pan troglodytes XP_530250 334 36683 S228 I S P V S N E S T S S S P G K
Rhesus Macaque Macaca mulatta XP_001118790 462 50301 S334 Q I P V K S P S P S S P A A V
Dog Lupus familis XP_851201 422 45800 S297 Q I P V K S P S P S S P A A A
Cat Felis silvestris
Mouse Mus musculus Q9R0A0 376 41189 S249 Q I P V K S S S P S S P A A V
Rat Rattus norvegicus Q642G4 376 40918 S249 Q I P V K S P S P S S P A A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510040 453 49031 E235 D I S P V S N E S A S S S P V
Chicken Gallus gallus XP_001234697 378 41628 S247 Q I P V K P S S P S N P V V A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688421 422 46346 S290 Q I P L K P G S L S N P P S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649253 280 30786 D204 E F S N F R S D L D A I K G L
Honey Bee Apis mellifera XP_624635 265 30025 E189 M I P Q L V Q E L K Q D L A S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798480 387 40504 A286 P R G Q T Y P A G S A A S D Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.5 74.8 83.4 N.A. 93 93.3 N.A. 57.8 80.4 N.A. 59.4 N.A. 24.1 20.1 N.A. 31.5
Protein Similarity: 100 88.5 76.4 85.3 N.A. 96 96.8 N.A. 64.2 89.4 N.A. 73.9 N.A. 40.3 38.4 N.A. 51.9
P-Site Identity: 100 33.3 100 93.3 N.A. 93.3 100 N.A. 26.6 60 N.A. 53.3 N.A. 0 20 N.A. 13.3
P-Site Similarity: 100 40 100 93.3 N.A. 93.3 100 N.A. 40 66.6 N.A. 73.3 N.A. 20 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 9 17 9 42 50 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 9 0 9 0 9 0 9 0 % D
% Glu: 9 0 0 0 0 0 9 17 0 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 9 0 9 0 0 0 0 17 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 75 0 0 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 59 0 0 0 0 9 0 0 9 0 9 % K
% Leu: 0 0 0 9 9 0 0 0 25 0 0 0 9 0 9 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 9 9 0 0 0 17 0 0 0 0 % N
% Pro: 9 0 75 9 0 17 42 0 50 0 0 59 17 9 0 % P
% Gln: 59 0 0 17 0 0 9 0 0 0 9 0 0 0 9 % Q
% Arg: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 17 0 9 50 25 67 9 75 59 17 17 9 9 % S
% Thr: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % T
% Val: 0 0 0 59 9 9 0 0 0 0 0 0 9 9 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _