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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ULK1
All Species:
3.94
Human Site:
S422
Identified Species:
7.22
UniProt:
O75385
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75385
NP_003556.1
1050
112601
S422
S
G
R
A
G
P
F
S
S
S
R
C
G
A
S
Chimpanzee
Pan troglodytes
XP_001148902
1004
106920
V380
A
Q
F
P
G
D
L
V
A
E
A
P
S
A
K
Rhesus Macaque
Macaca mulatta
XP_001105326
958
102155
R354
Q
N
Y
Q
R
I
E
R
N
L
Q
S
P
T
Q
Dog
Lupus familis
XP_534635
1032
110603
F402
P
S
G
R
A
G
P
F
S
S
R
C
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
O70405
1051
112444
S422
S
G
R
P
G
P
F
S
S
N
R
Y
G
A
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508434
1038
113312
R395
C
Q
P
S
L
S
P
R
S
E
T
A
P
I
P
Chicken
Gallus gallus
Q5ZJH6
468
53047
Frog
Xenopus laevis
Q4V7Q6
468
53109
Zebra Danio
Brachydanio rerio
XP_002665971
974
105808
R368
S
Q
G
K
T
P
P
R
S
P
S
F
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648601
835
90628
Q231
E
L
K
S
Y
Y
E
Q
N
A
N
L
A
P
K
Honey Bee
Apis mellifera
XP_624950
752
82281
K148
L
L
S
H
N
C
G
K
A
C
P
Q
P
H
Q
Nematode Worm
Caenorhab. elegans
Q23023
856
94874
L252
S
P
N
L
R
D
L
L
L
R
L
L
K
R
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX99
932
102644
V328
E
D
L
F
N
H
P
V
V
T
E
P
I
P
G
Conservation
Percent
Protein Identity:
100
84.2
89.1
87.9
N.A.
89.8
N.A.
N.A.
52.1
22.4
22
57.3
N.A.
34.3
36.6
33.6
N.A.
Protein Similarity:
100
86.1
89.7
91.2
N.A.
92.7
N.A.
N.A.
63.9
31.8
31.7
69.1
N.A.
47.7
49.3
47.9
N.A.
P-Site Identity:
100
13.3
0
40
N.A.
80
N.A.
N.A.
6.6
0
0
26.6
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
26.6
13.3
40
N.A.
86.6
N.A.
N.A.
13.3
0
0
33.3
N.A.
26.6
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
0
0
16
8
8
8
8
24
0
% A
% Cys:
8
0
0
0
0
8
0
0
0
8
0
16
0
0
0
% C
% Asp:
0
8
0
0
0
16
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
0
0
0
0
16
0
0
16
8
0
0
0
0
% E
% Phe:
0
0
8
8
0
0
16
8
0
0
0
8
0
0
0
% F
% Gly:
0
16
16
0
24
8
8
0
0
0
0
0
24
0
8
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
8
8
0
0
0
8
0
0
0
0
8
0
16
% K
% Leu:
8
16
8
8
8
0
16
8
8
8
8
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
16
0
0
0
16
8
8
0
0
0
8
% N
% Pro:
8
8
8
16
0
24
31
0
0
8
8
16
24
16
8
% P
% Gln:
8
24
0
8
0
0
0
8
0
0
8
8
0
0
16
% Q
% Arg:
0
0
16
8
16
0
0
24
0
8
24
0
0
8
0
% R
% Ser:
31
8
8
16
0
8
0
16
39
16
8
8
16
8
31
% S
% Thr:
0
0
0
0
8
0
0
0
0
8
8
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
16
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
8
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _