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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ULK1 All Species: 13.64
Human Site: S623 Identified Species: 25
UniProt: O75385 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75385 NP_003556.1 1050 112601 S623 P L P P I L G S P T K A V P S
Chimpanzee Pan troglodytes XP_001148902 1004 106920 P584 V R P K L P K P P T D P L G A
Rhesus Macaque Macaca mulatta XP_001105326 958 102155 L551 T P S S Q N L L A L L A R Q G
Dog Lupus familis XP_534635 1032 110603 S603 P L P P I L G S P T K A L P A
Cat Felis silvestris
Mouse Mus musculus O70405 1051 112444 S622 P L P P I L G S P T K A G P S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508434 1038 113312 S595 P L P T I I G S P T K A T A P
Chicken Gallus gallus Q5ZJH6 468 53047 T61 A S V E N L L T E I E I L K T
Frog Xenopus laevis Q4V7Q6 468 53109 E61 A V E N L L T E I E I L K T V
Zebra Danio Brachydanio rerio XP_002665971 974 105808 L565 E L M Q R N P L P T I L G S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648601 835 90628 R428 K P V P A P A R R Q V A R P G
Honey Bee Apis mellifera XP_624950 752 82281 I345 N T Q Q V K Y I K Q A S R E A
Nematode Worm Caenorhab. elegans Q23023 856 94874 R449 P V V Q R I E R P D Q L P R R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RX99 932 102644 Q525 E V N A L A D Q I S M Y P Q Q
Conservation
Percent
Protein Identity: 100 84.2 89.1 87.9 N.A. 89.8 N.A. N.A. 52.1 22.4 22 57.3 N.A. 34.3 36.6 33.6 N.A.
Protein Similarity: 100 86.1 89.7 91.2 N.A. 92.7 N.A. N.A. 63.9 31.8 31.7 69.1 N.A. 47.7 49.3 47.9 N.A.
P-Site Identity: 100 20 6.6 86.6 N.A. 93.3 N.A. N.A. 66.6 6.6 6.6 20 N.A. 20 0 13.3 N.A.
P-Site Similarity: 100 40 6.6 100 N.A. 93.3 N.A. N.A. 73.3 33.3 20 20 N.A. 20 20 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 8 8 8 0 8 0 8 47 0 8 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % D
% Glu: 16 0 8 8 0 0 8 8 8 8 8 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 31 0 0 0 0 0 16 8 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 31 16 0 8 16 8 16 8 0 0 0 % I
% Lys: 8 0 0 8 0 8 8 0 8 0 31 0 8 8 0 % K
% Leu: 0 39 0 0 24 39 16 16 0 8 8 24 24 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 8 0 8 8 8 16 0 0 0 0 0 0 0 0 0 % N
% Pro: 39 16 39 31 0 16 8 8 54 0 0 8 16 31 16 % P
% Gln: 0 0 8 24 8 0 0 8 0 16 8 0 0 16 8 % Q
% Arg: 0 8 0 0 16 0 0 16 8 0 0 0 24 8 8 % R
% Ser: 0 8 8 8 0 0 0 31 0 8 0 8 0 8 16 % S
% Thr: 8 8 0 8 0 0 8 8 0 47 0 0 8 8 8 % T
% Val: 8 24 24 0 8 0 0 0 0 0 8 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _