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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CS All Species: 31.21
Human Site: S29 Identified Species: 52.82
UniProt: O75390 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75390 NP_004068.2 466 51712 S29 A A R H A S A S S T N L K D I
Chimpanzee Pan troglodytes XP_001153202 466 51724 S29 A A R H A S A S S T N L K D I
Rhesus Macaque Macaca mulatta XP_001098147 621 67563 S184 A A R H A S A S S T N L K D I
Dog Lupus familis XP_531634 466 51770 S29 A A R H A S A S S T N L K D I
Cat Felis silvestris
Mouse Mus musculus Q9CZU6 464 51718 S29 A A R H A S A S S T N L K D V
Rat Rattus norvegicus Q8VHF5 466 51848 S29 A A R H A S A S S T N L K D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P23007 433 47314 G29 K T F R Q Q H G G T A L G Q I
Frog Xenopus laevis Q7ZWZ5 468 51729 S32 A A R Q A S S S T N L K D V L
Zebra Danio Brachydanio rerio Q7ZVY5 468 51733 S32 A A R N A S A S T N L K D V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W401 464 51556 D30 Y V R M I A A D G K S L R D V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34575 468 51522 G31 P L S T S A E G S T N L K E V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P20115 474 52764 L41 Q S S T D L D L K S Q L Q E L
Baker's Yeast Sacchar. cerevisiae P00890 479 53342 S41 A R H Y S S A S E Q T L K E R
Red Bread Mold Neurospora crassa P34085 469 51970 K34 A A R C Y S S K T Q T L K E R
Conservation
Percent
Protein Identity: 100 99.7 74.2 96.7 N.A. 93.9 94.6 N.A. N.A. 83.6 88 87.6 N.A. 70.1 N.A. 67.3 N.A.
Protein Similarity: 100 99.7 74.5 98 N.A. 97.4 97.8 N.A. N.A. 86 95.3 95.3 N.A. 81.3 N.A. 80.7 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. N.A. 20 40 46.6 N.A. 26.6 N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 20 60 66.6 N.A. 53.3 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 58.6 59.7 60.7
Protein Similarity: N.A. N.A. N.A. 75.7 76.6 78.4
P-Site Identity: N.A. N.A. N.A. 6.6 40 40
P-Site Similarity: N.A. N.A. N.A. 40 60 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 72 65 0 0 58 15 65 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 8 0 0 0 0 15 50 0 % D
% Glu: 0 0 0 0 0 0 8 0 8 0 0 0 0 29 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 15 15 0 0 0 8 0 0 % G
% His: 0 0 8 43 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 43 % I
% Lys: 8 0 0 0 0 0 0 8 8 8 0 15 65 0 0 % K
% Leu: 0 8 0 0 0 8 0 8 0 0 15 86 0 0 22 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 15 50 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 8 8 8 0 0 0 15 8 0 8 8 0 % Q
% Arg: 0 8 72 8 0 0 0 0 0 0 0 0 8 0 15 % R
% Ser: 0 8 15 0 15 72 15 65 50 8 8 0 0 0 0 % S
% Thr: 0 8 0 15 0 0 0 0 22 58 15 0 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 0 15 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _