KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CS
All Species:
37.27
Human Site:
S451
Identified Species:
63.08
UniProt:
O75390
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75390
NP_004068.2
466
51712
S451
F
P
L
E
R
P
K
S
M
S
T
E
G
L
M
Chimpanzee
Pan troglodytes
XP_001153202
466
51724
S451
F
P
L
E
R
P
K
S
M
S
T
E
G
L
M
Rhesus Macaque
Macaca mulatta
XP_001098147
621
67563
S606
F
P
L
E
R
P
K
S
M
S
T
E
G
L
M
Dog
Lupus familis
XP_531634
466
51770
S451
F
P
L
E
R
P
K
S
M
S
T
D
G
L
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU6
464
51718
P445
W
S
R
A
L
G
F
P
L
E
R
P
K
S
M
Rat
Rattus norvegicus
Q8VHF5
466
51848
S451
F
P
L
E
R
P
K
S
M
S
T
D
G
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23007
433
47314
P418
W
S
R
A
L
G
F
P
L
E
R
P
K
S
M
Frog
Xenopus laevis
Q7ZWZ5
468
51729
S453
F
P
L
E
R
P
K
S
M
S
T
D
G
L
M
Zebra Danio
Brachydanio rerio
Q7ZVY5
468
51733
S453
F
P
L
E
R
P
K
S
M
S
T
D
G
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W401
464
51556
P446
W
D
R
A
L
G
L
P
I
E
R
P
K
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34575
468
51522
S453
L
P
L
E
R
P
K
S
H
S
T
D
G
L
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P20115
474
52764
S458
L
A
L
E
R
P
K
S
V
T
M
D
W
L
E
Baker's Yeast
Sacchar. cerevisiae
P00890
479
53342
S462
A
P
I
E
R
P
K
S
F
S
T
E
K
Y
K
Red Bread Mold
Neurospora crassa
P34085
469
51970
G448
L
I
I
D
R
A
V
G
A
P
I
E
R
P
K
Conservation
Percent
Protein Identity:
100
99.7
74.2
96.7
N.A.
93.9
94.6
N.A.
N.A.
83.6
88
87.6
N.A.
70.1
N.A.
67.3
N.A.
Protein Similarity:
100
99.7
74.5
98
N.A.
97.4
97.8
N.A.
N.A.
86
95.3
95.3
N.A.
81.3
N.A.
80.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
6.6
93.3
N.A.
N.A.
6.6
93.3
93.3
N.A.
0
N.A.
73.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
N.A.
20
100
100
N.A.
13.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.6
59.7
60.7
Protein Similarity:
N.A.
N.A.
N.A.
75.7
76.6
78.4
P-Site Identity:
N.A.
N.A.
N.A.
46.6
60
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
66.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
22
0
8
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
0
43
0
0
0
% D
% Glu:
0
0
0
72
0
0
0
0
0
22
0
36
0
0
8
% E
% Phe:
50
0
0
0
0
0
15
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
22
0
8
0
0
0
0
58
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
15
0
0
0
0
0
8
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
72
0
0
0
0
0
29
0
15
% K
% Leu:
22
0
65
0
22
0
8
0
15
0
0
0
0
65
0
% L
% Met:
0
0
0
0
0
0
0
0
50
0
8
0
0
0
65
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
65
0
0
0
72
0
22
0
8
0
22
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
22
0
79
0
0
0
0
0
22
0
8
0
0
% R
% Ser:
0
15
0
0
0
0
0
72
0
65
0
0
0
22
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
65
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% V
% Trp:
22
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _