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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CS
All Species:
40.91
Human Site:
Y199
Identified Species:
69.23
UniProt:
O75390
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75390
NP_004068.2
466
51712
Y199
T
K
Y
W
E
L
I
Y
E
D
S
M
D
L
I
Chimpanzee
Pan troglodytes
XP_001153202
466
51724
Y199
T
K
Y
W
E
L
I
Y
E
D
S
M
D
L
I
Rhesus Macaque
Macaca mulatta
XP_001098147
621
67563
Y354
T
K
Y
W
E
L
I
Y
E
D
S
M
D
L
I
Dog
Lupus familis
XP_531634
466
51770
Y199
T
K
Y
W
E
L
I
Y
E
D
C
M
D
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU6
464
51718
Y199
A
K
Y
W
E
L
I
Y
E
D
C
M
D
L
I
Rat
Rattus norvegicus
Q8VHF5
466
51848
Y199
T
K
Y
W
E
L
I
Y
E
D
C
M
D
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23007
433
47314
L182
A
M
D
L
I
A
K
L
P
C
V
A
A
K
I
Frog
Xenopus laevis
Q7ZWZ5
468
51729
Y201
A
K
Y
W
E
L
V
Y
E
D
S
M
D
L
I
Zebra Danio
Brachydanio rerio
Q7ZVY5
468
51733
Y201
A
K
Y
W
E
F
V
Y
E
D
S
M
D
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W401
464
51556
Y200
S
K
Y
W
E
Y
V
Y
E
D
S
M
D
L
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34575
468
51522
Y201
A
S
Y
W
E
Y
A
Y
E
D
S
M
D
L
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P20115
474
52764
Y207
S
K
F
W
E
P
T
Y
E
D
C
L
N
L
I
Baker's Yeast
Sacchar. cerevisiae
P00890
479
53342
F211
K
E
Y
W
S
Y
T
F
E
D
S
L
D
L
L
Red Bread Mold
Neurospora crassa
P34085
469
51970
F204
K
E
Y
W
G
Y
T
F
E
D
S
M
D
L
I
Conservation
Percent
Protein Identity:
100
99.7
74.2
96.7
N.A.
93.9
94.6
N.A.
N.A.
83.6
88
87.6
N.A.
70.1
N.A.
67.3
N.A.
Protein Similarity:
100
99.7
74.5
98
N.A.
97.4
97.8
N.A.
N.A.
86
95.3
95.3
N.A.
81.3
N.A.
80.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
6.6
86.6
80
N.A.
80
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
6.6
93.3
86.6
N.A.
93.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.6
59.7
60.7
Protein Similarity:
N.A.
N.A.
N.A.
75.7
76.6
78.4
P-Site Identity:
N.A.
N.A.
N.A.
53.3
46.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
0
0
0
0
8
8
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
29
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
93
0
0
86
0
0
% D
% Glu:
0
15
0
0
79
0
0
0
93
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
8
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
43
0
0
0
0
0
0
0
86
% I
% Lys:
15
72
0
0
0
0
8
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
8
0
50
0
8
0
0
0
15
0
93
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
79
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
15
8
0
0
8
0
0
0
0
0
65
0
0
0
0
% S
% Thr:
36
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
22
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
86
0
0
29
0
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _