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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CS
All Species:
47.27
Human Site:
Y69
Identified Species:
80
UniProt:
O75390
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75390
NP_004068.2
466
51712
Y69
Q
I
T
V
D
M
M
Y
G
G
M
R
G
M
K
Chimpanzee
Pan troglodytes
XP_001153202
466
51724
Y69
Q
I
T
V
D
M
M
Y
G
G
M
R
G
M
K
Rhesus Macaque
Macaca mulatta
XP_001098147
621
67563
Y224
Q
I
T
V
D
M
M
Y
G
G
M
R
G
M
K
Dog
Lupus familis
XP_531634
466
51770
Y69
Q
I
T
V
D
M
M
Y
G
G
M
R
G
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU6
464
51718
Y69
Q
I
T
V
D
M
M
Y
G
G
M
R
G
M
K
Rat
Rattus norvegicus
Q8VHF5
466
51848
Y69
Q
I
T
V
D
M
M
Y
G
G
M
R
G
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23007
433
47314
R65
L
D
P
D
E
G
I
R
F
R
G
F
S
I
P
Frog
Xenopus laevis
Q7ZWZ5
468
51729
Y71
Q
V
T
V
D
M
V
Y
G
G
M
R
G
M
K
Zebra Danio
Brachydanio rerio
Q7ZVY5
468
51733
Y71
Q
I
T
V
D
M
V
Y
G
G
M
R
G
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W401
464
51556
Y70
E
T
T
I
D
M
M
Y
G
G
M
R
G
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34575
468
51522
Y71
N
V
N
I
D
M
I
Y
G
G
M
R
S
M
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P20115
474
52764
I77
N
I
T
V
D
M
V
I
G
G
M
R
G
M
T
Baker's Yeast
Sacchar. cerevisiae
P00890
479
53342
Y81
E
V
L
L
E
Q
A
Y
G
G
M
R
G
I
K
Red Bread Mold
Neurospora crassa
P34085
469
51970
Y74
K
V
T
L
D
Q
V
Y
G
G
A
R
G
I
K
Conservation
Percent
Protein Identity:
100
99.7
74.2
96.7
N.A.
93.9
94.6
N.A.
N.A.
83.6
88
87.6
N.A.
70.1
N.A.
67.3
N.A.
Protein Similarity:
100
99.7
74.5
98
N.A.
97.4
97.8
N.A.
N.A.
86
95.3
95.3
N.A.
81.3
N.A.
80.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
86.6
86.6
N.A.
73.3
N.A.
60
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
100
100
N.A.
93.3
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.6
59.7
60.7
Protein Similarity:
N.A.
N.A.
N.A.
75.7
76.6
78.4
P-Site Identity:
N.A.
N.A.
N.A.
73.3
46.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
80
80
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
86
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
15
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
93
93
8
0
86
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
58
0
15
0
0
15
8
0
0
0
0
0
29
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
86
% K
% Leu:
8
0
8
15
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
79
50
0
0
0
86
0
0
65
0
% M
% Asn:
15
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
58
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
93
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% S
% Thr:
0
8
79
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
29
0
65
0
0
29
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _