KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22B
All Species:
23.64
Human Site:
S168
Identified Species:
40
UniProt:
O75396
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75396
NP_004883.2
215
24741
S168
E
A
L
S
A
L
D
S
K
A
N
N
L
S
S
Chimpanzee
Pan troglodytes
XP_001144507
153
17785
A108
L
S
A
L
D
S
K
A
N
N
L
S
S
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533025
215
24738
S168
E
A
L
S
A
L
D
S
K
A
N
N
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH47
307
35006
A230
E
D
L
N
Y
I
I
A
F
F
L
G
T
A
A
Rat
Rattus norvegicus
Q642F4
307
34883
A230
E
D
F
S
Y
M
I
A
F
F
L
G
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJW4
215
24699
S168
E
A
L
S
A
L
D
S
K
A
N
N
L
S
S
Frog
Xenopus laevis
NP_001080905
220
25346
S173
E
A
L
S
A
L
D
S
K
A
N
N
L
S
T
Zebra Danio
Brachydanio rerio
Q7SXP0
215
24671
S168
E
A
L
S
A
L
D
S
K
A
S
N
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569863
211
24627
T166
T
V
L
A
E
L
D
T
K
T
Q
N
L
S
M
Honey Bee
Apis mellifera
XP_396838
213
24746
T168
T
V
L
S
E
L
D
T
K
T
Q
N
L
S
M
Nematode Worm
Caenorhab. elegans
NP_508198
214
24261
N167
E
A
L
N
I
L
E
N
R
A
S
E
L
S
G
Sea Urchin
Strong. purpuratus
XP_795453
216
25141
N170
V
C
L
E
E
L
D
N
K
A
S
N
L
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
E169
E
K
L
D
Q
V
S
E
M
S
S
R
L
T
S
Baker's Yeast
Sacchar. cerevisiae
P22214
214
25039
D166
D
S
L
D
K
M
S
D
M
S
S
S
L
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.1
N.A.
99.5
N.A.
28
28
N.A.
N.A.
98.1
90.9
90.2
N.A.
57.2
59.5
47.4
69.4
Protein Similarity:
100
71.1
N.A.
100
N.A.
43.6
43.6
N.A.
N.A.
99
95.4
94.8
N.A.
73.4
79.5
68.8
84.2
P-Site Identity:
100
6.6
N.A.
100
N.A.
13.3
13.3
N.A.
N.A.
100
93.3
93.3
N.A.
46.6
53.3
46.6
53.3
P-Site Similarity:
100
26.6
N.A.
100
N.A.
46.6
40
N.A.
N.A.
100
100
100
N.A.
60
60
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.8
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
8
8
36
0
0
22
0
50
0
0
0
15
15
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
15
8
0
58
8
0
0
0
0
0
0
0
% D
% Glu:
65
0
0
8
22
0
8
8
0
0
0
8
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
15
15
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
15
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
8
0
58
0
0
0
0
8
0
% K
% Leu:
8
0
86
8
0
65
0
0
0
0
22
0
79
8
0
% L
% Met:
0
0
0
0
0
15
0
0
15
0
0
0
0
0
15
% M
% Asn:
0
0
0
15
0
0
0
15
8
8
29
58
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
15
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
15
0
50
0
8
15
36
0
15
36
15
8
65
43
% S
% Thr:
15
0
0
0
0
0
0
15
0
15
0
0
15
8
15
% T
% Val:
8
15
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _