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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22B
All Species:
43.03
Human Site:
Y110
Identified Species:
72.82
UniProt:
O75396
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75396
NP_004883.2
215
24741
Y110
V
P
T
V
S
R
P
Y
S
F
I
E
F
D
T
Chimpanzee
Pan troglodytes
XP_001144507
153
17785
K59
E
F
D
T
F
I
Q
K
T
K
K
L
Y
I
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533025
215
24738
Y110
V
P
T
V
S
R
P
Y
S
F
I
E
F
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH47
307
35006
Y110
T
N
T
A
V
R
P
Y
C
F
I
E
F
D
N
Rat
Rattus norvegicus
Q642F4
307
34883
Y110
T
N
T
A
V
R
P
Y
C
F
I
E
F
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJW4
215
24699
Y110
V
P
T
V
S
R
P
Y
S
F
I
E
F
D
T
Frog
Xenopus laevis
NP_001080905
220
25346
Y115
V
P
T
V
S
R
P
Y
S
F
I
E
F
D
N
Zebra Danio
Brachydanio rerio
Q7SXP0
215
24671
Y110
V
P
T
V
S
R
P
Y
S
F
I
E
F
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569863
211
24627
Y110
V
N
S
V
T
R
P
Y
A
F
I
E
F
D
V
Honey Bee
Apis mellifera
XP_396838
213
24746
Y110
V
N
S
V
T
R
P
Y
S
F
I
E
F
N
T
Nematode Worm
Caenorhab. elegans
NP_508198
214
24261
Y110
I
E
Q
V
V
R
P
Y
H
F
L
E
F
D
K
Sea Urchin
Strong. purpuratus
XP_795453
216
25141
Y112
V
P
T
I
S
R
P
Y
S
F
I
E
F
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
Y111
I
E
T
A
A
R
P
Y
A
F
I
K
F
D
T
Baker's Yeast
Sacchar. cerevisiae
P22214
214
25039
F116
Q
F
V
N
F
D
N
F
L
Q
M
T
K
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.1
N.A.
99.5
N.A.
28
28
N.A.
N.A.
98.1
90.9
90.2
N.A.
57.2
59.5
47.4
69.4
Protein Similarity:
100
71.1
N.A.
100
N.A.
43.6
43.6
N.A.
N.A.
99
95.4
94.8
N.A.
73.4
79.5
68.8
84.2
P-Site Identity:
100
0
N.A.
100
N.A.
60
60
N.A.
N.A.
100
93.3
100
N.A.
66.6
73.3
53.3
93.3
P-Site Similarity:
100
13.3
N.A.
100
N.A.
60
60
N.A.
N.A.
100
93.3
100
N.A.
86.6
93.3
66.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.8
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
22
8
0
0
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
0
0
0
79
8
% D
% Glu:
8
15
0
0
0
0
0
0
0
0
0
79
0
0
0
% E
% Phe:
0
15
0
0
15
0
0
8
0
86
0
0
86
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
15
0
0
8
0
8
0
0
0
0
79
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
8
8
8
8
8
8
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
29
0
8
0
0
8
0
0
0
0
0
0
8
22
% N
% Pro:
0
43
0
0
0
0
86
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
0
8
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
15
0
43
0
0
0
50
0
0
0
0
0
8
% S
% Thr:
15
0
65
8
15
0
0
0
8
0
0
8
0
0
50
% T
% Val:
58
0
8
58
22
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _