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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22B
All Species:
24.24
Human Site:
Y186
Identified Species:
41.03
UniProt:
O75396
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75396
NP_004883.2
215
24741
Y186
K
Y
R
Q
D
A
K
Y
L
N
M
R
S
T
Y
Chimpanzee
Pan troglodytes
XP_001144507
153
17785
N126
R
Q
D
A
K
Y
L
N
M
R
S
T
Y
A
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533025
215
24738
Y186
K
Y
R
Q
D
A
K
Y
L
N
M
R
S
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH47
307
35006
Y248
Q
C
Y
L
L
V
Y
Y
T
S
W
R
N
V
K
Rat
Rattus norvegicus
Q642F4
307
34883
Y248
Q
C
Y
L
L
V
Y
Y
T
S
W
R
N
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJW4
215
24699
Y186
K
Y
R
Q
D
A
K
Y
L
N
M
R
S
T
Y
Frog
Xenopus laevis
NP_001080905
220
25346
Y191
K
Y
R
Q
D
A
K
Y
L
N
M
R
S
T
Y
Zebra Danio
Brachydanio rerio
Q7SXP0
215
24671
Y186
K
Y
R
S
D
A
K
Y
L
N
T
R
S
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569863
211
24627
L184
K
Y
K
K
D
A
K
L
L
N
R
K
S
M
Y
Honey Bee
Apis mellifera
XP_396838
213
24746
Y186
K
Y
K
K
D
A
T
Y
L
N
S
K
S
M
Y
Nematode Worm
Caenorhab. elegans
NP_508198
214
24261
A185
K
Y
R
D
D
A
K
A
L
N
R
R
S
T
I
Sea Urchin
Strong. purpuratus
XP_795453
216
25141
N188
K
Y
R
Q
D
A
K
N
L
N
L
R
S
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
D187
I
Y
A
D
K
A
K
D
L
N
R
Q
A
L
I
Baker's Yeast
Sacchar. cerevisiae
P22214
214
25039
K184
R
Y
R
K
S
A
Q
K
I
N
F
D
L
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.1
N.A.
99.5
N.A.
28
28
N.A.
N.A.
98.1
90.9
90.2
N.A.
57.2
59.5
47.4
69.4
Protein Similarity:
100
71.1
N.A.
100
N.A.
43.6
43.6
N.A.
N.A.
99
95.4
94.8
N.A.
73.4
79.5
68.8
84.2
P-Site Identity:
100
0
N.A.
100
N.A.
13.3
13.3
N.A.
N.A.
100
100
86.6
N.A.
60
60
73.3
73.3
P-Site Similarity:
100
13.3
N.A.
100
N.A.
33.3
33.3
N.A.
N.A.
100
100
86.6
N.A.
80
80
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.8
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
79
0
8
0
0
0
0
8
8
0
% A
% Cys:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
15
65
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
22
% I
% Lys:
65
0
15
22
15
0
65
8
0
0
0
15
0
0
22
% K
% Leu:
0
0
0
15
15
0
8
8
72
0
8
0
8
15
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
29
0
0
15
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
79
0
0
15
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
8
0
36
0
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
15
0
58
0
0
0
0
0
0
8
22
65
0
8
0
% R
% Ser:
0
0
0
8
8
0
0
0
0
15
15
0
65
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
15
0
8
8
0
43
0
% T
% Val:
0
0
0
0
0
15
0
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
79
15
0
0
8
15
58
0
0
0
0
8
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _