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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TACC1
All Species:
10.3
Human Site:
S454
Identified Species:
22.67
UniProt:
O75410
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75410
NP_001116296.1
805
87794
S454
H
V
N
E
I
L
E
S
P
K
K
A
K
S
R
Chimpanzee
Pan troglodytes
XP_001171659
806
87880
S455
H
V
N
E
I
L
E
S
P
K
K
A
K
S
R
Rhesus Macaque
Macaca mulatta
XP_001094596
713
77960
T382
C
K
V
K
K
H
E
T
Q
S
L
A
L
D
A
Dog
Lupus familis
XP_848665
800
87410
S449
H
I
N
E
I
L
E
S
P
K
K
A
K
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6Y685
774
83933
A440
T
S
S
G
F
C
P
A
T
G
N
H
V
N
E
Rat
Rattus norvegicus
Q4KLH6
1403
160982
R800
H
L
M
E
D
I
K
R
L
K
Q
D
K
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506072
798
87999
A447
E
D
M
K
K
G
K
A
S
P
K
K
A
K
S
Chicken
Gallus gallus
XP_428807
620
67438
P289
K
V
K
Q
Y
E
T
P
A
L
V
L
D
G
C
Frog
Xenopus laevis
Q9PTG8
931
102522
F581
K
L
A
T
E
A
D
F
L
L
A
A
D
M
D
Zebra Danio
Brachydanio rerio
XP_694073
852
95238
K501
E
K
L
T
E
K
L
K
S
D
G
T
P
E
Q
Tiger Blowfish
Takifugu rubipres
NP_001011696
863
95190
P513
K
G
S
Y
T
F
D
P
D
N
F
D
D
S
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
84.7
85.5
N.A.
73.9
20.8
N.A.
69.8
50
27
42.6
38.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
85.8
91.1
N.A.
81.6
32.6
N.A.
78.1
59
44.1
55
53.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
93.3
N.A.
0
26.6
N.A.
6.6
6.6
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
20
53.3
N.A.
26.6
13.3
20
6.6
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
19
10
0
10
46
10
0
19
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
10
0
19
0
10
10
0
19
28
10
10
% D
% Glu:
19
0
0
37
19
10
37
0
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
10
10
0
10
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
10
0
10
0
0
0
10
10
0
0
10
0
% G
% His:
37
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
10
0
0
28
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
28
19
10
19
19
10
19
10
0
37
37
10
37
10
0
% K
% Leu:
0
19
10
0
0
28
10
0
19
19
10
10
10
0
0
% L
% Met:
0
0
19
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
28
0
0
0
0
0
0
10
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
10
19
28
10
0
0
10
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
10
0
0
10
10
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
28
% R
% Ser:
0
10
19
0
0
0
0
28
19
10
0
0
0
37
10
% S
% Thr:
10
0
0
19
10
0
10
10
10
0
0
10
0
0
0
% T
% Val:
0
28
10
0
0
0
0
0
0
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _