KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME6
All Species:
32.12
Human Site:
S131
Identified Species:
64.24
UniProt:
O75414
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75414
NP_005784.1
186
21142
S131
T
R
N
T
T
H
G
S
D
S
V
V
S
A
S
Chimpanzee
Pan troglodytes
XP_516435
186
21124
S131
T
R
N
T
T
H
G
S
D
S
V
V
S
A
S
Rhesus Macaque
Macaca mulatta
XP_001112721
183
20351
S128
T
R
N
T
T
H
G
S
D
S
V
V
S
A
S
Dog
Lupus familis
XP_533843
316
35199
S261
T
R
N
T
T
H
G
S
D
S
V
I
S
A
S
Cat
Felis silvestris
Mouse
Mus musculus
O88425
189
21759
S131
T
R
N
T
T
H
G
S
D
S
V
V
S
A
S
Rat
Rattus norvegicus
O88426
175
20093
S120
T
R
N
T
T
H
G
S
D
S
V
V
S
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424474
186
21359
S131
T
R
N
T
T
H
G
S
D
S
P
A
S
A
S
Frog
Xenopus laevis
NP_001089757
139
16072
L85
G
P
M
Q
A
Y
I
L
A
H
E
D
A
I
Q
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
R120
K
Y
G
L
T
D
T
R
N
T
T
H
G
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572965
151
17192
V97
P
T
K
V
F
R
A
V
Y
S
D
P
N
C
I
Honey Bee
Apis mellifera
XP_001119864
131
15277
S77
T
F
M
C
S
G
P
S
D
I
H
I
L
A
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200902
185
21210
S130
T
R
N
A
T
H
G
S
D
S
P
E
T
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
84.4
54.7
N.A.
88.3
86.5
N.A.
N.A.
66.1
54.8
59.1
N.A.
37.6
36
N.A.
52.6
Protein Similarity:
100
100
88.7
56.9
N.A.
91
88.7
N.A.
N.A.
80.1
63.9
74.7
N.A.
52.1
49.4
N.A.
62.9
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
0
6.6
N.A.
6.6
26.6
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
13.3
26.6
N.A.
13.3
40
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
9
0
9
0
0
9
9
75
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
9
0
0
75
0
9
9
0
0
17
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% E
% Phe:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
0
0
9
67
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
67
0
0
0
9
9
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
9
0
17
0
9
9
% I
% Lys:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
9
0
0
0
0
9
0
0
% L
% Met:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
67
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
9
9
0
0
0
0
9
0
0
0
17
9
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
67
0
0
0
9
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
75
0
75
0
0
59
9
59
% S
% Thr:
75
9
0
59
75
0
9
0
0
9
9
0
9
0
0
% T
% Val:
0
0
0
9
0
0
0
9
0
0
50
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _