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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME6
All Species:
31.52
Human Site:
T122
Identified Species:
63.03
UniProt:
O75414
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75414
NP_005784.1
186
21142
T122
I
R
G
S
F
G
L
T
D
T
R
N
T
T
H
Chimpanzee
Pan troglodytes
XP_516435
186
21124
T122
I
R
G
S
F
G
L
T
D
T
R
N
T
T
H
Rhesus Macaque
Macaca mulatta
XP_001112721
183
20351
T119
I
R
G
S
F
G
L
T
D
T
R
N
T
T
H
Dog
Lupus familis
XP_533843
316
35199
T252
I
R
G
S
F
G
L
T
D
T
R
N
T
T
H
Cat
Felis silvestris
Mouse
Mus musculus
O88425
189
21759
T122
I
R
G
S
L
G
L
T
D
T
R
N
T
T
H
Rat
Rattus norvegicus
O88426
175
20093
T111
I
R
G
S
L
G
L
T
D
T
R
N
T
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424474
186
21359
T122
I
R
G
A
Y
G
L
T
D
T
R
N
T
T
H
Frog
Xenopus laevis
NP_001089757
139
16072
S76
Q
R
L
V
E
F
M
S
S
G
P
M
Q
A
Y
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
R111
F
S
S
P
E
T
L
R
G
K
Y
G
L
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572965
151
17192
L88
I
Q
K
W
R
S
L
L
G
P
T
K
V
F
R
Honey Bee
Apis mellifera
XP_001119864
131
15277
L68
E
K
F
F
Y
N
R
L
L
T
F
M
C
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200902
185
21210
T121
I
R
G
E
H
G
L
T
D
T
R
N
A
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
84.4
54.7
N.A.
88.3
86.5
N.A.
N.A.
66.1
54.8
59.1
N.A.
37.6
36
N.A.
52.6
Protein Similarity:
100
100
88.7
56.9
N.A.
91
88.7
N.A.
N.A.
80.1
63.9
74.7
N.A.
52.1
49.4
N.A.
62.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
6.6
13.3
N.A.
13.3
6.6
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
26.6
13.3
N.A.
20
26.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
9
% D
% Glu:
9
0
0
9
17
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
9
9
34
9
0
0
0
0
9
0
0
9
0
% F
% Gly:
0
0
67
0
0
67
0
0
17
9
0
9
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
67
% H
% Ile:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
9
0
9
0
0
0
% K
% Leu:
0
0
9
0
17
0
84
17
9
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
17
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
67
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
9
9
0
0
0
0
% P
% Gln:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
75
0
0
9
0
9
9
0
0
67
0
0
0
9
% R
% Ser:
0
9
9
50
0
9
0
9
9
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
9
0
67
0
75
9
0
59
75
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
0
0
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _