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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NME6 All Species: 33.03
Human Site: T128 Identified Species: 66.06
UniProt: O75414 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75414 NP_005784.1 186 21142 T128 L T D T R N T T H G S D S V V
Chimpanzee Pan troglodytes XP_516435 186 21124 T128 L T D T R N T T H G S D S V V
Rhesus Macaque Macaca mulatta XP_001112721 183 20351 T125 L T D T R N T T H G S D S V V
Dog Lupus familis XP_533843 316 35199 T258 L T D T R N T T H G S D S V I
Cat Felis silvestris
Mouse Mus musculus O88425 189 21759 T128 L T D T R N T T H G S D S V V
Rat Rattus norvegicus O88426 175 20093 T117 L T D T R N T T H G S D S V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424474 186 21359 T128 L T D T R N T T H G S D S P A
Frog Xenopus laevis NP_001089757 139 16072 A82 M S S G P M Q A Y I L A H E D
Zebra Danio Brachydanio rerio Q6DI51 175 20593 T117 L R G K Y G L T D T R N T T H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572965 151 17192 F94 L L G P T K V F R A V Y S D P
Honey Bee Apis mellifera XP_001119864 131 15277 S74 R L L T F M C S G P S D I H I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200902 185 21210 T127 L T D T R N A T H G S D S P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 84.4 54.7 N.A. 88.3 86.5 N.A. N.A. 66.1 54.8 59.1 N.A. 37.6 36 N.A. 52.6
Protein Similarity: 100 100 88.7 56.9 N.A. 91 88.7 N.A. N.A. 80.1 63.9 74.7 N.A. 52.1 49.4 N.A. 62.9
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 86.6 0 13.3 N.A. 13.3 20 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 20 26.6 N.A. 13.3 33.3 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 9 0 9 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 67 0 0 0 0 0 9 0 0 75 0 9 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % E
% Phe: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 9 0 9 0 0 9 67 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 67 0 0 0 9 9 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 17 % I
% Lys: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 84 17 9 0 0 0 9 0 0 0 9 0 0 0 0 % L
% Met: 9 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 67 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 9 9 0 0 0 0 9 0 0 0 17 9 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 9 9 0 0 67 0 0 0 9 0 9 0 0 0 0 % R
% Ser: 0 9 9 0 0 0 0 9 0 0 75 0 75 0 0 % S
% Thr: 0 67 0 75 9 0 59 75 0 9 0 0 9 9 0 % T
% Val: 0 0 0 0 0 0 9 0 0 0 9 0 0 50 42 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _