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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME6
All Species:
28.18
Human Site:
Y154
Identified Species:
56.36
UniProt:
O75414
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75414
NP_005784.1
186
21142
Y154
D
F
S
E
Q
R
W
Y
E
E
E
E
P
Q
L
Chimpanzee
Pan troglodytes
XP_516435
186
21124
Y154
D
F
S
E
Q
R
W
Y
E
E
E
E
P
Q
L
Rhesus Macaque
Macaca mulatta
XP_001112721
183
20351
Y151
D
F
S
E
Q
R
W
Y
E
E
E
E
P
Q
L
Dog
Lupus familis
XP_533843
316
35199
Y284
D
F
S
E
Q
R
W
Y
E
E
E
E
P
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
O88425
189
21759
Y154
D
F
S
E
Q
R
W
Y
E
E
E
E
P
Q
L
Rat
Rattus norvegicus
O88426
175
20093
Y143
D
F
S
E
Q
R
W
Y
E
E
E
E
P
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424474
186
21359
Y154
E
F
N
E
Q
L
W
Y
Q
Q
E
E
P
R
L
Frog
Xenopus laevis
NP_001089757
139
16072
I108
T
K
V
F
R
A
R
I
V
A
P
E
T
V
R
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
F143
I
S
F
F
F
P
E
F
S
A
E
E
W
M
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572965
151
17192
S120
T
R
N
A
C
H
G
S
D
S
E
A
S
A
L
Honey Bee
Apis mellifera
XP_001119864
131
15277
V100
N
L
M
G
P
T
K
V
Y
E
A
Q
Y
I
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200902
185
21210
L153
E
F
N
I
P
L
W
L
E
R
E
E
P
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
84.4
54.7
N.A.
88.3
86.5
N.A.
N.A.
66.1
54.8
59.1
N.A.
37.6
36
N.A.
52.6
Protein Similarity:
100
100
88.7
56.9
N.A.
91
88.7
N.A.
N.A.
80.1
63.9
74.7
N.A.
52.1
49.4
N.A.
62.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
60
6.6
13.3
N.A.
13.3
6.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
13.3
26.6
N.A.
26.6
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
0
17
9
9
0
9
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
17
0
0
59
0
0
9
0
59
59
84
84
0
0
0
% E
% Phe:
0
67
9
17
9
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
0
0
0
9
0
0
0
0
0
9
0
% I
% Lys:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
17
0
9
0
0
0
0
0
9
67
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
9
% M
% Asn:
9
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
17
9
0
0
0
0
9
0
67
0
0
% P
% Gln:
0
0
0
0
59
0
0
0
9
9
0
9
0
50
0
% Q
% Arg:
0
9
0
0
9
50
9
0
0
9
0
0
0
9
9
% R
% Ser:
0
9
50
0
0
0
0
9
9
9
0
0
9
0
0
% S
% Thr:
17
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
9
0
0
0
0
9
9
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
67
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _