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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME6
All Species:
9.39
Human Site:
Y176
Identified Species:
18.79
UniProt:
O75414
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75414
NP_005784.1
186
21142
Y176
S
P
E
G
G
V
H
Y
V
A
G
T
G
G
L
Chimpanzee
Pan troglodytes
XP_516435
186
21124
Y176
S
P
E
G
G
V
H
Y
V
A
G
T
G
G
L
Rhesus Macaque
Macaca mulatta
XP_001112721
183
20351
Y173
S
P
E
G
G
V
H
Y
V
A
G
T
G
D
L
Dog
Lupus familis
XP_533843
316
35199
C306
S
P
E
G
G
I
H
C
A
A
G
P
G
G
P
Cat
Felis silvestris
Mouse
Mus musculus
O88425
189
21759
C176
S
P
E
E
G
I
H
C
A
A
E
T
G
G
H
Rat
Rattus norvegicus
O88426
175
20093
C165
S
P
E
E
G
I
H
C
A
A
E
T
G
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424474
186
21359
C176
N
A
E
K
R
V
H
C
V
I
R
G
E
E
T
Frog
Xenopus laevis
NP_001089757
139
16072
S130
T
R
N
T
T
H
G
S
G
L
I
T
F
R
H
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
E165
L
G
H
T
E
Y
N
E
E
S
Q
I
H
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572965
151
17192
G142
P
E
F
D
A
A
V
G
S
R
Q
A
K
R
E
Honey Bee
Apis mellifera
XP_001119864
131
15277
N122
F
G
L
S
D
T
R
N
A
T
H
G
S
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200902
185
21210
I175
C
K
D
G
G
I
H
I
P
K
P
T
F
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
84.4
54.7
N.A.
88.3
86.5
N.A.
N.A.
66.1
54.8
59.1
N.A.
37.6
36
N.A.
52.6
Protein Similarity:
100
100
88.7
56.9
N.A.
91
88.7
N.A.
N.A.
80.1
63.9
74.7
N.A.
52.1
49.4
N.A.
62.9
P-Site Identity:
100
100
93.3
66.6
N.A.
60
60
N.A.
N.A.
26.6
6.6
0
N.A.
0
0
N.A.
26.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
66.6
66.6
N.A.
N.A.
33.3
13.3
20
N.A.
0
0
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
9
0
0
34
50
0
9
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
9
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
9
59
17
9
0
0
9
9
0
17
0
9
17
9
% E
% Phe:
9
0
9
0
0
0
0
0
0
0
0
0
17
0
0
% F
% Gly:
0
17
0
42
59
0
9
9
9
0
34
17
50
42
0
% G
% His:
0
0
9
0
0
9
67
0
0
0
9
0
9
0
17
% H
% Ile:
0
0
0
0
0
34
0
9
0
9
9
9
0
0
0
% I
% Lys:
0
9
0
9
0
0
0
0
0
9
0
0
9
0
0
% K
% Leu:
9
0
9
0
0
0
0
0
0
9
0
0
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
9
9
0
0
0
0
0
0
0
% N
% Pro:
9
50
0
0
0
0
0
0
9
0
9
9
0
0
17
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
9
% Q
% Arg:
0
9
0
0
9
0
9
0
0
9
9
0
0
17
0
% R
% Ser:
50
0
0
9
0
0
0
9
9
9
0
0
9
0
0
% S
% Thr:
9
0
0
17
9
9
0
0
0
9
0
59
0
17
17
% T
% Val:
0
0
0
0
0
34
9
0
34
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _