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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME6
All Species:
25.45
Human Site:
Y60
Identified Species:
50.91
UniProt:
O75414
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75414
NP_005784.1
186
21142
Y60
K
E
D
C
Q
R
F
Y
R
E
H
E
G
R
F
Chimpanzee
Pan troglodytes
XP_516435
186
21124
Y60
K
E
D
C
Q
R
F
Y
R
E
H
E
G
R
F
Rhesus Macaque
Macaca mulatta
XP_001112721
183
20351
S57
S
L
P
N
S
F
R
S
S
L
F
A
G
R
F
Dog
Lupus familis
XP_533843
316
35199
Y190
K
E
E
C
Q
K
F
Y
Q
E
H
E
G
R
F
Cat
Felis silvestris
Mouse
Mus musculus
O88425
189
21759
Y60
L
E
D
C
R
R
F
Y
R
E
H
E
G
R
F
Rat
Rattus norvegicus
O88426
175
20093
Y49
P
E
D
C
R
R
F
Y
R
E
H
E
G
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424474
186
21359
Y60
R
E
Q
S
R
R
F
Y
R
E
H
A
G
Q
F
Frog
Xenopus laevis
NP_001089757
139
16072
L14
V
R
P
L
Q
L
T
L
A
L
I
K
P
D
A
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
A49
K
D
L
I
W
R
K
A
D
S
E
M
F
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572965
151
17192
I26
M
Q
Q
I
R
A
L
I
S
Q
N
F
T
I
L
Honey Bee
Apis mellifera
XP_001119864
131
15277
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200902
185
21210
Y59
K
S
D
A
A
R
F
Y
A
E
H
E
G
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
84.4
54.7
N.A.
88.3
86.5
N.A.
N.A.
66.1
54.8
59.1
N.A.
37.6
36
N.A.
52.6
Protein Similarity:
100
100
88.7
56.9
N.A.
91
88.7
N.A.
N.A.
80.1
63.9
74.7
N.A.
52.1
49.4
N.A.
62.9
P-Site Identity:
100
100
20
80
N.A.
86.6
86.6
N.A.
N.A.
60
6.6
13.3
N.A.
0
0
N.A.
73.3
P-Site Similarity:
100
100
20
100
N.A.
93.3
93.3
N.A.
N.A.
80
13.3
20
N.A.
26.6
0
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
0
9
17
0
0
17
0
0
17
% A
% Cys:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
42
0
0
0
0
0
9
0
0
0
0
9
0
% D
% Glu:
0
50
9
0
0
0
0
0
0
59
9
50
0
0
0
% E
% Phe:
0
0
0
0
0
9
59
0
0
0
9
9
9
0
67
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
0
9
0
0
9
0
0
9
0
% I
% Lys:
42
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% K
% Leu:
9
9
9
9
0
9
9
9
0
17
0
0
0
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
9
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
9
17
0
34
0
0
0
9
9
0
0
0
9
0
% Q
% Arg:
9
9
0
0
34
59
9
0
42
0
0
0
0
59
0
% R
% Ser:
9
9
0
9
9
0
0
9
17
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _