KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME6
All Species:
30
Human Site:
Y69
Identified Species:
60
UniProt:
O75414
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75414
NP_005784.1
186
21142
Y69
E
H
E
G
R
F
F
Y
Q
R
L
V
E
F
M
Chimpanzee
Pan troglodytes
XP_516435
186
21124
Y69
E
H
E
G
R
F
F
Y
Q
R
L
V
E
F
M
Rhesus Macaque
Macaca mulatta
XP_001112721
183
20351
Y66
L
F
A
G
R
F
F
Y
Q
R
V
V
E
F
M
Dog
Lupus familis
XP_533843
316
35199
Y199
E
H
E
G
R
F
F
Y
Q
R
L
V
E
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
O88425
189
21759
Y69
E
H
E
G
R
F
F
Y
Q
R
L
V
E
F
M
Rat
Rattus norvegicus
O88426
175
20093
Y58
E
H
E
G
R
F
F
Y
Q
R
L
V
E
F
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424474
186
21359
Y69
E
H
A
G
Q
F
F
Y
Q
R
L
V
E
F
M
Frog
Xenopus laevis
NP_001089757
139
16072
A23
L
I
K
P
D
A
V
A
H
P
V
I
S
E
A
Zebra Danio
Brachydanio rerio
Q6DI51
175
20593
H58
S
E
M
F
Y
A
E
H
S
G
R
F
F
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572965
151
17192
Q35
Q
N
F
T
I
L
D
Q
K
E
V
C
I
T
K
Honey Bee
Apis mellifera
XP_001119864
131
15277
K15
Q
L
T
L
A
I
I
K
P
H
I
V
K
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200902
185
21210
Y68
E
H
E
G
R
F
F
Y
N
R
L
V
G
F
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
84.4
54.7
N.A.
88.3
86.5
N.A.
N.A.
66.1
54.8
59.1
N.A.
37.6
36
N.A.
52.6
Protein Similarity:
100
100
88.7
56.9
N.A.
91
88.7
N.A.
N.A.
80.1
63.9
74.7
N.A.
52.1
49.4
N.A.
62.9
P-Site Identity:
100
100
73.3
93.3
N.A.
100
100
N.A.
N.A.
86.6
0
6.6
N.A.
0
6.6
N.A.
86.6
P-Site Similarity:
100
100
80
100
N.A.
100
100
N.A.
N.A.
93.3
20
13.3
N.A.
26.6
26.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
17
0
9
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
59
9
50
0
0
0
9
0
0
9
0
0
59
9
0
% E
% Phe:
0
9
9
9
0
67
67
0
0
0
0
9
9
67
0
% F
% Gly:
0
0
0
67
0
0
0
0
0
9
0
0
9
0
0
% G
% His:
0
59
0
0
0
0
0
9
9
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
9
9
0
0
0
9
9
9
0
0
% I
% Lys:
0
0
9
0
0
0
0
9
9
0
0
0
9
0
9
% K
% Leu:
17
9
0
9
0
9
0
0
0
0
59
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
67
% M
% Asn:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
9
9
0
0
0
0
9
% P
% Gln:
17
0
0
0
9
0
0
9
59
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
59
0
0
0
0
67
9
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
9
0
0
0
9
9
0
% S
% Thr:
0
0
9
9
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
25
75
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
67
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _