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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NME6 All Species: 26.36
Human Site: Y84 Identified Species: 52.73
UniProt: O75414 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75414 NP_005784.1 186 21142 Y84 A S G P I R A Y I L A H K D A
Chimpanzee Pan troglodytes XP_516435 186 21124 Y84 A S G P I R A Y I L A H K D A
Rhesus Macaque Macaca mulatta XP_001112721 183 20351 Y81 A S G P I R A Y I L A H K D A
Dog Lupus familis XP_533843 316 35199 Y214 A S G P I R A Y I L A R K D A
Cat Felis silvestris
Mouse Mus musculus O88425 189 21759 Y84 T S G P I R A Y I L A H K D A
Rat Rattus norvegicus O88426 175 20093 Y73 T S G P I R A Y I L A H K D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424474 186 21359 Y84 A S G P M W A Y I L A H E N A
Frog Xenopus laevis NP_001089757 139 16072 N38 V H E K I L E N N F L I V K R
Zebra Danio Brachydanio rerio Q6DI51 175 20593 S73 R L V E F M S S G P M R A Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572965 151 17192 A50 E L S E R F Y A E H K G K F F
Honey Bee Apis mellifera XP_001119864 131 15277 D30 F V L Q K I R D L I I D N N L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200902 185 21210 Q83 T S G P M C A Q I L A G D N A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 84.4 54.7 N.A. 88.3 86.5 N.A. N.A. 66.1 54.8 59.1 N.A. 37.6 36 N.A. 52.6
Protein Similarity: 100 100 88.7 56.9 N.A. 91 88.7 N.A. N.A. 80.1 63.9 74.7 N.A. 52.1 49.4 N.A. 62.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 73.3 6.6 0 N.A. 6.6 0 N.A. 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 6.6 6.6 N.A. 6.6 20 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 0 0 0 0 0 67 9 0 0 67 0 9 0 67 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 9 0 0 0 9 9 50 0 % D
% Glu: 9 0 9 17 0 0 9 0 9 0 0 0 9 0 0 % E
% Phe: 9 0 0 0 9 9 0 0 0 9 0 0 0 9 9 % F
% Gly: 0 0 67 0 0 0 0 0 9 0 0 17 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 9 0 50 0 0 0 % H
% Ile: 0 0 0 0 59 9 0 0 67 9 9 9 0 0 9 % I
% Lys: 0 0 0 9 9 0 0 0 0 0 9 0 59 9 0 % K
% Leu: 0 17 9 0 0 9 0 0 9 67 9 0 0 0 9 % L
% Met: 0 0 0 0 17 9 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 0 0 0 9 25 0 % N
% Pro: 0 0 0 67 0 0 0 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 9 50 9 0 0 0 0 17 0 0 9 % R
% Ser: 0 67 9 0 0 0 9 9 0 0 0 0 0 0 0 % S
% Thr: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 9 9 9 0 0 0 0 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 59 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _