KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC45L
All Species:
39.39
Human Site:
S264
Identified Species:
66.67
UniProt:
O75419
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75419
NP_003495.1
566
65569
S264
E
D
E
E
N
T
L
S
V
D
C
T
R
I
S
Chimpanzee
Pan troglodytes
XP_514980
566
65532
S264
E
D
E
E
N
T
L
S
V
D
C
T
R
I
S
Rhesus Macaque
Macaca mulatta
XP_001104872
566
65509
S264
E
D
E
E
N
T
L
S
V
D
C
T
R
I
S
Dog
Lupus familis
XP_543547
586
67352
S284
E
D
E
E
H
A
L
S
V
D
C
T
R
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1X9
566
65366
S264
E
A
E
E
N
M
L
S
V
D
C
T
R
I
S
Rat
Rattus norvegicus
NP_001099336
570
65921
S268
E
A
E
E
N
M
L
S
V
D
C
T
R
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415070
566
65691
S264
E
D
E
E
N
S
L
S
I
D
C
M
R
I
A
Frog
Xenopus laevis
Q9YHZ6
567
65426
S265
E
D
E
E
N
S
L
S
I
D
C
M
R
I
A
Zebra Danio
Brachydanio rerio
NP_998551
572
65871
S270
E
D
E
E
N
S
L
S
I
D
C
M
R
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569880
575
65872
A280
N
D
Q
N
T
M
S
A
S
K
I
T
F
E
N
Honey Bee
Apis mellifera
XP_393560
561
64352
Q259
G
T
E
D
D
K
P
Q
Q
Q
S
A
V
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180929
568
65050
S265
E
D
E
E
N
T
V
S
V
N
T
M
K
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189146
596
67533
K290
K
I
T
S
V
T
L
K
D
G
T
K
V
R
A
Baker's Yeast
Sacchar. cerevisiae
Q08032
650
74231
T312
S
S
R
N
S
V
K
T
P
D
T
L
T
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.2
90.2
N.A.
91.6
91
N.A.
N.A.
83.2
78.3
74.3
N.A.
40
43.4
N.A.
55.4
Protein Similarity:
100
100
99.6
94.3
N.A.
95.9
95.2
N.A.
N.A.
94.1
90.4
90.3
N.A.
64.8
64.4
N.A.
75.1
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
73.3
73.3
73.3
N.A.
13.3
6.6
N.A.
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
93.3
93.3
93.3
N.A.
33.3
20
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
8
0
8
0
0
0
8
0
0
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% C
% Asp:
0
65
0
8
8
0
0
0
8
72
0
0
0
0
0
% D
% Glu:
72
0
79
72
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
22
0
8
0
0
72
8
% I
% Lys:
8
0
0
0
0
8
8
8
0
8
0
8
8
8
0
% K
% Leu:
0
0
0
0
0
0
72
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
22
0
0
0
0
0
29
0
0
0
% M
% Asn:
8
0
0
15
65
0
0
0
0
8
0
0
0
0
22
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
8
8
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
65
8
0
% R
% Ser:
8
8
0
8
8
22
8
72
8
0
8
0
0
0
50
% S
% Thr:
0
8
8
0
8
36
0
8
0
0
22
50
8
0
0
% T
% Val:
0
0
0
0
8
8
8
0
50
0
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _