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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC45L
All Species:
47.27
Human Site:
S545
Identified Species:
80
UniProt:
O75419
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75419
NP_003495.1
566
65569
S545
L
H
N
H
F
D
L
S
V
I
E
L
K
A
E
Chimpanzee
Pan troglodytes
XP_514980
566
65532
S545
L
H
N
H
F
D
L
S
V
I
E
L
K
A
E
Rhesus Macaque
Macaca mulatta
XP_001104872
566
65509
S545
L
H
N
H
F
D
L
S
V
I
E
L
K
A
E
Dog
Lupus familis
XP_543547
586
67352
S565
L
H
N
H
F
D
L
S
V
I
E
L
K
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1X9
566
65366
S545
L
H
N
Y
F
D
L
S
V
I
E
L
K
A
E
Rat
Rattus norvegicus
NP_001099336
570
65921
S549
L
H
N
Y
F
D
L
S
V
I
E
L
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415070
566
65691
S545
L
H
N
H
F
D
M
S
I
I
E
L
K
T
E
Frog
Xenopus laevis
Q9YHZ6
567
65426
S546
L
H
N
H
F
D
M
S
I
I
E
L
R
T
E
Zebra Danio
Brachydanio rerio
NP_998551
572
65871
S551
L
H
D
H
F
D
T
S
V
I
E
L
K
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569880
575
65872
V555
Q
D
F
F
E
P
A
V
V
Q
L
R
Q
S
D
Honey Bee
Apis mellifera
XP_393560
561
64352
T540
E
A
D
Y
F
D
T
T
I
I
R
L
K
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180929
568
65050
S547
L
H
N
H
F
D
S
S
I
M
E
L
K
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189146
596
67533
S576
F
H
E
L
F
E
S
S
W
I
V
L
D
A
S
Baker's Yeast
Sacchar. cerevisiae
Q08032
650
74231
S628
R
I
D
N
F
E
S
S
I
I
E
I
R
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.2
90.2
N.A.
91.6
91
N.A.
N.A.
83.2
78.3
74.3
N.A.
40
43.4
N.A.
55.4
Protein Similarity:
100
100
99.6
94.3
N.A.
95.9
95.2
N.A.
N.A.
94.1
90.4
90.3
N.A.
64.8
64.4
N.A.
75.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
80
73.3
80
N.A.
6.6
40
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
86.6
N.A.
26.6
66.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
0
0
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
22
0
0
79
0
0
0
0
0
0
8
0
8
% D
% Glu:
8
0
8
0
8
15
0
0
0
0
79
0
0
0
79
% E
% Phe:
8
0
8
8
93
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
79
0
58
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
36
86
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
0
% K
% Leu:
72
0
0
8
0
0
43
0
0
0
8
86
0
0
0
% L
% Met:
0
0
0
0
0
0
15
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
65
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
8
8
15
8
0
% R
% Ser:
0
0
0
0
0
0
22
86
0
0
0
0
0
8
8
% S
% Thr:
0
0
0
0
0
0
15
8
0
0
0
0
0
22
0
% T
% Val:
0
0
0
0
0
0
0
8
58
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _