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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC45L
All Species:
39.7
Human Site:
T293
Identified Species:
67.18
UniProt:
O75419
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75419
NP_003495.1
566
65569
T293
L
H
D
S
L
C
N
T
S
Y
T
A
A
R
F
Chimpanzee
Pan troglodytes
XP_514980
566
65532
T293
L
H
D
S
L
C
N
T
S
Y
T
A
A
R
F
Rhesus Macaque
Macaca mulatta
XP_001104872
566
65509
T293
L
H
D
S
L
C
N
T
S
Y
T
A
A
R
F
Dog
Lupus familis
XP_543547
586
67352
T313
L
H
D
S
L
C
N
T
C
Y
T
A
A
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1X9
566
65366
T293
L
H
E
S
L
Y
N
T
S
Y
T
A
A
R
F
Rat
Rattus norvegicus
NP_001099336
570
65921
T297
L
H
E
S
L
Y
N
T
S
Y
T
A
A
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415070
566
65691
T293
L
Y
E
S
L
C
N
T
S
Y
T
S
A
T
L
Frog
Xenopus laevis
Q9YHZ6
567
65426
S294
L
Y
E
S
I
C
N
S
C
Y
T
S
A
T
L
Zebra Danio
Brachydanio rerio
NP_998551
572
65871
S299
L
Y
E
S
I
C
N
S
C
Y
T
S
C
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569880
575
65872
S309
S
M
R
Y
S
R
Y
S
S
C
Q
L
K
L
W
Honey Bee
Apis mellifera
XP_393560
561
64352
H288
T
V
E
A
S
L
R
H
T
I
P
T
A
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180929
568
65050
S294
I
F
E
S
L
K
H
S
S
Y
T
A
C
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189146
596
67533
L319
M
L
L
R
E
W
T
L
F
D
S
M
L
C
S
Baker's Yeast
Sacchar. cerevisiae
Q08032
650
74231
S341
L
Y
D
S
F
Y
Y
S
N
Y
V
N
A
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.2
90.2
N.A.
91.6
91
N.A.
N.A.
83.2
78.3
74.3
N.A.
40
43.4
N.A.
55.4
Protein Similarity:
100
100
99.6
94.3
N.A.
95.9
95.2
N.A.
N.A.
94.1
90.4
90.3
N.A.
64.8
64.4
N.A.
75.1
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
66.6
46.6
46.6
N.A.
6.6
6.6
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
80
N.A.
20
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
50
72
0
0
% A
% Cys:
0
0
0
0
0
50
0
0
22
8
0
0
15
8
0
% C
% Asp:
0
0
36
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
50
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
8
0
0
0
8
0
0
0
0
0
50
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
43
0
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
15
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% K
% Leu:
72
8
8
0
58
8
0
8
0
0
0
8
8
8
29
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
65
0
8
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
8
0
8
8
0
0
0
0
0
0
43
0
% R
% Ser:
8
0
0
79
15
0
0
36
58
0
8
22
0
8
15
% S
% Thr:
8
0
0
0
0
0
8
50
8
0
72
8
0
15
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
29
0
8
0
22
15
0
0
79
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _