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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC45L
All Species:
22.12
Human Site:
T426
Identified Species:
37.44
UniProt:
O75419
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75419
NP_003495.1
566
65569
T426
A
K
K
Q
L
R
A
T
Q
Q
T
I
A
S
C
Chimpanzee
Pan troglodytes
XP_514980
566
65532
T426
A
K
K
Q
L
R
A
T
Q
Q
T
I
A
S
C
Rhesus Macaque
Macaca mulatta
XP_001104872
566
65509
T426
A
K
K
Q
L
R
A
T
Q
Q
T
I
A
S
C
Dog
Lupus familis
XP_543547
586
67352
T446
A
K
K
Q
L
R
A
T
Q
Q
T
I
A
S
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1X9
566
65366
T426
A
K
K
H
L
Q
A
T
Q
Q
T
I
A
S
C
Rat
Rattus norvegicus
NP_001099336
570
65921
T430
A
K
K
H
L
Q
A
T
Q
Q
T
I
A
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415070
566
65691
I426
A
K
K
Q
L
R
A
I
Q
Q
T
V
A
S
C
Frog
Xenopus laevis
Q9YHZ6
567
65426
I427
G
K
K
L
L
C
A
I
Q
Q
T
V
A
S
C
Zebra Danio
Brachydanio rerio
NP_998551
572
65871
I432
A
K
K
K
L
K
A
I
Q
Q
T
V
A
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569880
575
65872
V439
A
K
L
L
H
A
A
V
F
R
Q
V
Q
S
S
Honey Bee
Apis mellifera
XP_393560
561
64352
I422
A
K
L
M
L
I
S
I
F
K
T
A
Q
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180929
568
65050
V427
S
K
L
Q
L
Q
A
V
V
I
Q
V
Q
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189146
596
67533
R459
Q
Q
A
I
K
V
Q
R
A
I
L
R
Q
G
S
Baker's Yeast
Sacchar. cerevisiae
Q08032
650
74231
V474
T
N
L
R
K
R
W
V
S
N
F
W
L
S
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.2
90.2
N.A.
91.6
91
N.A.
N.A.
83.2
78.3
74.3
N.A.
40
43.4
N.A.
55.4
Protein Similarity:
100
100
99.6
94.3
N.A.
95.9
95.2
N.A.
N.A.
94.1
90.4
90.3
N.A.
64.8
64.4
N.A.
75.1
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
86.6
66.6
73.3
N.A.
26.6
26.6
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
73.3
93.3
N.A.
40
46.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
0
8
0
0
8
79
0
8
0
0
8
65
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
65
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
15
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
29
0
15
0
43
0
0
8
% I
% Lys:
0
86
65
8
15
8
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
29
15
79
0
0
0
0
0
8
0
8
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
43
0
22
8
0
65
65
15
0
29
0
0
% Q
% Arg:
0
0
0
8
0
43
0
8
0
8
0
8
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
0
8
0
0
0
0
86
15
% S
% Thr:
8
0
0
0
0
0
0
43
0
0
72
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
22
8
0
0
36
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _