KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRCH4
All Species:
0.91
Human Site:
S457
Identified Species:
2.86
UniProt:
O75427
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75427
NP_002310.2
683
73450
S457
T
Q
A
M
H
N
G
S
P
K
S
S
A
S
Q
Chimpanzee
Pan troglodytes
XP_001167143
779
86714
S549
D
D
S
A
L
C
T
S
D
D
R
P
N
A
L
Rhesus Macaque
Macaca mulatta
XP_001086884
683
73602
P457
T
Q
A
T
H
N
G
P
P
K
S
S
A
S
Q
Dog
Lupus familis
XP_546954
669
71773
R454
R
P
L
G
S
I
Q
R
P
N
S
F
L
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q921G6
680
73145
G456
S
T
Q
A
T
C
N
G
P
P
K
S
S
T
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514226
691
77204
N462
E
L
Q
D
T
T
M
N
G
Q
I
Q
L
E
T
Chicken
Gallus gallus
Q5ZLN0
603
67457
L388
P
P
V
T
A
M
T
L
P
S
E
S
R
I
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
P344
H
N
Q
I
S
K
I
P
I
G
I
F
S
K
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
97
79.8
N.A.
85.3
N.A.
N.A.
40.5
22.1
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
100
57.6
97.9
84.1
N.A.
91.6
N.A.
N.A.
54.2
39.6
N.A.
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
P-Site Identity:
100
6.6
86.6
13.3
N.A.
13.3
N.A.
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
86.6
20
N.A.
33.3
N.A.
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
25
13
0
0
0
0
0
0
0
25
13
13
% A
% Cys:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
13
0
13
0
0
0
0
13
13
0
0
0
0
0
% D
% Glu:
13
0
0
0
0
0
0
0
0
0
13
0
0
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
25
0
13
0
% F
% Gly:
0
0
0
13
0
0
25
13
13
13
0
0
0
0
0
% G
% His:
13
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
0
13
13
0
13
0
25
0
0
13
0
% I
% Lys:
0
0
0
0
0
13
0
0
0
25
13
0
0
13
0
% K
% Leu:
0
13
13
0
13
0
0
13
0
0
0
0
25
0
13
% L
% Met:
0
0
0
13
0
13
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
25
13
13
0
13
0
0
13
0
13
% N
% Pro:
13
25
0
0
0
0
0
25
63
13
0
13
0
0
0
% P
% Gln:
0
25
38
0
0
0
13
0
0
13
0
13
0
0
25
% Q
% Arg:
13
0
0
0
0
0
0
13
0
0
13
0
13
0
13
% R
% Ser:
13
0
13
0
25
0
0
25
0
13
38
50
25
25
0
% S
% Thr:
25
13
0
25
25
13
25
0
0
0
0
0
0
13
25
% T
% Val:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _