KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX2
All Species:
31.21
Human Site:
Y65
Identified Species:
57.22
UniProt:
O75431
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75431
NP_006545.1
263
29763
Y65
V
C
R
A
N
A
E
Y
M
S
P
S
G
K
V
Chimpanzee
Pan troglodytes
XP_001153838
253
28805
S59
N
A
E
Y
M
S
P
S
G
K
V
P
F
I
H
Rhesus Macaque
Macaca mulatta
XP_001095310
263
29673
Y65
V
C
R
A
N
A
E
Y
M
S
P
S
G
K
V
Dog
Lupus familis
XP_535974
267
30347
Y65
V
C
R
A
N
A
E
Y
M
S
P
S
G
K
V
Cat
Felis silvestris
Mouse
Mus musculus
O88441
263
29740
Y65
V
C
R
A
N
A
E
Y
M
S
P
S
G
K
V
Rat
Rattus norvegicus
NP_001008287
263
29700
Y65
V
C
R
A
N
A
E
Y
M
S
P
S
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515208
248
28473
V56
F
I
H
V
G
N
Q
V
V
S
E
L
G
P
I
Chicken
Gallus gallus
XP_421989
276
31162
Y65
V
C
R
A
N
A
E
Y
M
S
P
S
G
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001098699
259
29233
Y65
M
Y
R
A
N
A
E
Y
M
S
P
S
G
K
I
Fruit Fly
Dros. melanogaster
NP_649161
269
31058
P70
A
N
A
E
H
M
S
P
G
G
R
M
T
K
L
Honey Bee
Apis mellifera
XP_001122107
264
30139
Y69
E
P
R
S
N
A
E
Y
M
S
P
S
G
R
V
Nematode Worm
Caenorhab. elegans
P34599
230
26066
L38
P
Y
L
N
D
Q
A
L
M
Y
D
F
A
D
C
Sea Urchin
Strong. purpuratus
XP_797071
268
30694
Q71
M
L
R
S
N
A
E
Q
M
S
P
S
G
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
99.6
93.2
N.A.
96.9
93.9
N.A.
76.4
84
N.A.
N.A.
78.7
42
50.3
32.7
47.7
Protein Similarity:
100
96.1
99.6
93.6
N.A.
98.4
96.5
N.A.
84
89.8
N.A.
N.A.
89.7
63.2
68.1
52
62.3
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
13.3
100
N.A.
N.A.
80
6.6
73.3
6.6
66.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
33.3
100
N.A.
N.A.
93.3
20
86.6
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
54
0
70
8
0
0
0
0
0
8
8
0
% A
% Cys:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
0
8
8
0
0
70
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
16
8
0
0
77
0
0
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
16
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
62
0
% K
% Leu:
0
8
8
0
0
0
0
8
0
0
0
8
0
0
8
% L
% Met:
16
0
0
0
8
8
0
0
77
0
0
8
0
0
0
% M
% Asn:
8
8
0
8
70
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
0
0
8
8
0
0
70
8
0
8
0
% P
% Gln:
0
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
70
0
0
0
0
0
0
0
8
0
0
8
0
% R
% Ser:
0
0
0
16
0
8
8
8
0
77
0
70
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
47
0
0
8
0
0
0
8
8
0
8
0
0
0
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
8
0
0
0
62
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _