KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCB
All Species:
14.24
Human Site:
S22
Identified Species:
20.89
UniProt:
O75439
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75439
NP_004270.2
489
54366
S22
R
R
R
L
W
G
F
S
E
S
L
L
I
R
G
Chimpanzee
Pan troglodytes
XP_001160333
489
54373
S22
R
R
R
L
W
G
F
S
E
S
F
L
I
R
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533104
513
56776
P46
A
G
R
A
S
R
P
P
R
V
W
V
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXT8
489
54596
T22
R
R
R
L
W
G
F
T
R
R
L
P
L
R
R
Rat
Rattus norvegicus
Q03346
489
54247
T22
G
R
R
L
W
G
F
T
R
R
L
P
L
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507859
495
54657
S28
G
R
R
P
L
W
R
S
A
E
A
F
V
G
G
Chicken
Gallus gallus
XP_415962
487
54047
A19
R
L
F
L
P
W
C
A
R
L
A
R
P
S
G
Frog
Xenopus laevis
NP_001085137
479
53355
V21
K
A
A
I
R
G
L
V
S
K
S
Q
P
I
G
Zebra Danio
Brachydanio rerio
NP_001012514
470
52313
L19
G
R
H
L
I
K
N
L
F
N
T
K
V
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650401
470
51856
V19
M
R
S
F
M
R
G
V
D
M
I
K
R
Y
K
Honey Bee
Apis mellifera
XP_393509
477
53330
N19
L
R
A
Y
S
N
K
N
S
L
V
K
I
Q
K
Nematode Worm
Caenorhab. elegans
P98080
471
51717
S24
S
Q
V
R
N
A
S
S
A
V
S
V
K
D
V
Sea Urchin
Strong. purpuratus
XP_001176813
476
53032
S19
L
S
R
F
A
T
K
S
H
A
G
R
N
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42290
531
59141
K62
D
H
A
A
E
I
I
K
N
K
I
K
K
L
E
Baker's Yeast
Sacchar. cerevisiae
P10507
462
51065
I19
T
R
R
L
L
S
T
I
S
S
Q
I
P
G
T
Red Bread Mold
Neurospora crassa
P11913
476
52538
R27
G
V
I
N
P
F
R
R
G
L
A
T
P
H
S
Conservation
Percent
Protein Identity:
100
99.3
N.A.
87.5
N.A.
90.1
89.7
N.A.
82.8
81.8
82.6
77.9
N.A.
66
62.5
38
70.7
Protein Similarity:
100
99.3
N.A.
91.2
N.A.
94.8
95
N.A.
90
89.7
88.9
85
N.A.
76.2
77.5
59.9
84.2
P-Site Identity:
100
93.3
N.A.
6.6
N.A.
60
53.3
N.A.
26.6
20
13.3
13.3
N.A.
6.6
13.3
6.6
20
P-Site Similarity:
100
93.3
N.A.
13.3
N.A.
73.3
66.6
N.A.
33.3
26.6
26.6
26.6
N.A.
20
33.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.1
43.3
48.2
Protein Similarity:
N.A.
N.A.
N.A.
63.8
61.9
66.6
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
19
13
7
7
0
7
13
7
19
0
0
7
13
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
7
0
0
0
13
7
0
0
0
0
7
% E
% Phe:
0
0
7
13
0
7
25
0
7
0
7
7
0
0
0
% F
% Gly:
25
7
0
0
0
32
7
0
7
0
7
0
0
13
38
% G
% His:
0
7
7
0
0
0
0
0
7
0
0
0
0
7
0
% H
% Ile:
0
0
7
7
7
7
7
7
0
0
13
7
19
13
0
% I
% Lys:
7
0
0
0
0
7
13
7
0
13
0
25
13
0
13
% K
% Leu:
13
7
0
44
13
0
7
7
0
19
19
13
13
7
0
% L
% Met:
7
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
7
7
7
7
7
0
0
7
0
7
% N
% Pro:
0
0
0
7
13
0
7
7
0
0
0
13
32
7
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
7
7
0
7
0
% Q
% Arg:
25
57
50
7
7
13
13
7
25
13
0
13
7
25
7
% R
% Ser:
7
7
7
0
13
7
7
32
19
19
13
0
0
7
7
% S
% Thr:
7
0
0
0
0
7
7
13
0
0
7
7
0
0
7
% T
% Val:
0
7
7
0
0
0
0
13
0
13
7
13
13
0
7
% V
% Trp:
0
0
0
0
25
13
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _