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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCB
All Species:
32.12
Human Site:
S71
Identified Species:
47.11
UniProt:
O75439
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75439
NP_004270.2
489
54366
S71
E
S
G
L
R
V
A
S
E
D
S
G
L
S
T
Chimpanzee
Pan troglodytes
XP_001160333
489
54373
S71
E
S
G
L
R
V
A
S
E
D
S
G
L
S
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533104
513
56776
S95
D
N
G
L
R
V
A
S
E
D
S
G
L
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXT8
489
54596
S71
E
N
G
L
R
V
A
S
E
N
S
G
L
S
T
Rat
Rattus norvegicus
Q03346
489
54247
S71
E
N
G
L
R
V
A
S
E
N
S
G
I
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507859
495
54657
S77
E
N
G
L
R
V
A
S
E
D
S
G
L
S
T
Chicken
Gallus gallus
XP_415962
487
54047
S68
E
N
G
L
Q
V
A
S
E
D
S
G
L
S
T
Frog
Xenopus laevis
NP_001085137
479
53355
T70
S
E
D
S
G
L
L
T
C
T
V
G
L
W
I
Zebra Danio
Brachydanio rerio
NP_001012514
470
52313
G68
G
L
S
T
C
T
V
G
L
W
I
D
A
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650401
470
51856
I68
T
A
T
V
G
L
W
I
D
A
G
S
R
S
E
Honey Bee
Apis mellifera
XP_393509
477
53330
V68
S
G
A
P
T
A
T
V
G
L
W
I
D
A
G
Nematode Worm
Caenorhab. elegans
P98080
471
51717
N73
E
T
G
S
R
F
E
N
E
K
N
N
G
V
A
Sea Urchin
Strong. purpuratus
XP_001176813
476
53032
V68
S
G
I
P
T
A
T
V
G
L
W
I
D
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42290
531
59141
E111
N
G
L
R
V
A
T
E
S
N
L
S
A
K
T
Baker's Yeast
Sacchar. cerevisiae
P10507
462
51065
T68
E
N
V
K
N
N
G
T
A
H
F
L
E
H
L
Red Bread Mold
Neurospora crassa
P11913
476
52538
T76
D
A
G
S
R
A
E
T
D
E
T
N
G
T
A
Conservation
Percent
Protein Identity:
100
99.3
N.A.
87.5
N.A.
90.1
89.7
N.A.
82.8
81.8
82.6
77.9
N.A.
66
62.5
38
70.7
Protein Similarity:
100
99.3
N.A.
91.2
N.A.
94.8
95
N.A.
90
89.7
88.9
85
N.A.
76.2
77.5
59.9
84.2
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
80
N.A.
93.3
86.6
13.3
0
N.A.
6.6
0
26.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
26.6
6.6
N.A.
33.3
6.6
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.1
43.3
48.2
Protein Similarity:
N.A.
N.A.
N.A.
63.8
61.9
66.6
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
7
0
0
25
44
0
7
7
0
0
13
13
13
% A
% Cys:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
13
0
7
0
0
0
0
0
13
32
0
7
13
0
0
% D
% Glu:
50
7
0
0
0
0
13
7
50
7
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
19
57
0
13
0
7
7
13
0
7
50
13
7
13
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% H
% Ile:
0
0
7
0
0
0
0
7
0
0
7
13
7
0
7
% I
% Lys:
0
0
0
7
0
0
0
0
0
7
0
0
0
7
0
% K
% Leu:
0
7
7
44
0
13
7
0
7
13
7
7
44
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
38
0
0
7
7
0
7
0
19
7
13
0
0
0
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
50
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
19
13
7
19
0
0
0
44
7
0
44
13
0
50
7
% S
% Thr:
7
7
7
7
13
7
19
19
0
7
7
0
0
7
50
% T
% Val:
0
0
7
7
7
44
7
13
0
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
7
13
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _