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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCB
All Species:
33.64
Human Site:
S89
Identified Species:
49.33
UniProt:
O75439
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75439
NP_004270.2
489
54366
S89
G
L
W
I
D
A
G
S
R
Y
E
N
E
K
N
Chimpanzee
Pan troglodytes
XP_001160333
489
54373
S89
G
L
W
I
D
A
G
S
R
Y
E
N
E
K
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533104
513
56776
S113
G
L
W
I
D
A
G
S
R
Y
E
N
E
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXT8
489
54596
S89
G
L
W
I
D
A
G
S
R
Y
E
N
E
K
N
Rat
Rattus norvegicus
Q03346
489
54247
S89
G
L
W
I
D
A
G
S
R
Y
E
N
E
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507859
495
54657
S95
G
L
W
I
D
A
G
S
R
Y
E
N
E
K
N
Chicken
Gallus gallus
XP_415962
487
54047
S86
G
L
W
I
D
A
G
S
R
Y
E
N
E
K
N
Frog
Xenopus laevis
NP_001085137
479
53355
N88
S
R
Y
E
N
Q
M
N
N
G
T
A
H
F
L
Zebra Danio
Brachydanio rerio
NP_001012514
470
52313
A86
N
E
H
N
N
G
T
A
H
F
L
E
H
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650401
470
51856
L86
N
N
G
V
A
H
F
L
E
H
M
A
F
K
G
Honey Bee
Apis mellifera
XP_393509
477
53330
V86
E
T
D
E
N
N
G
V
A
H
F
M
E
H
M
Nematode Worm
Caenorhab. elegans
P98080
471
51717
T91
E
R
L
I
H
K
G
T
G
K
R
A
S
A
A
Sea Urchin
Strong. purpuratus
XP_001176813
476
53032
V86
E
N
A
K
N
N
G
V
A
H
Y
L
E
H
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42290
531
59141
S129
G
V
W
I
D
A
G
S
R
F
E
S
D
E
T
Baker's Yeast
Sacchar. cerevisiae
P10507
462
51065
Q86
G
T
Q
N
R
S
Q
Q
G
I
E
L
E
I
E
Red Bread Mold
Neurospora crassa
P11913
476
52538
T94
E
H
L
A
F
K
G
T
T
K
R
T
Q
Q
Q
Conservation
Percent
Protein Identity:
100
99.3
N.A.
87.5
N.A.
90.1
89.7
N.A.
82.8
81.8
82.6
77.9
N.A.
66
62.5
38
70.7
Protein Similarity:
100
99.3
N.A.
91.2
N.A.
94.8
95
N.A.
90
89.7
88.9
85
N.A.
76.2
77.5
59.9
84.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
0
N.A.
6.6
13.3
13.3
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
20
20
N.A.
20
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.1
43.3
48.2
Protein Similarity:
N.A.
N.A.
N.A.
63.8
61.9
66.6
P-Site Identity:
N.A.
N.A.
N.A.
60
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
7
50
0
7
13
0
0
19
0
7
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
50
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
25
7
0
13
0
0
0
0
7
0
57
7
63
7
7
% E
% Phe:
0
0
0
0
7
0
7
0
0
13
7
0
7
7
0
% F
% Gly:
57
0
7
0
0
7
75
0
13
7
0
0
0
0
7
% G
% His:
0
7
7
0
7
7
0
0
7
19
0
0
13
13
0
% H
% Ile:
0
0
0
57
0
0
0
0
0
7
0
0
0
7
0
% I
% Lys:
0
0
0
7
0
13
0
0
0
13
0
0
0
50
0
% K
% Leu:
0
44
13
0
0
0
0
7
0
0
7
13
0
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
0
7
7
0
7
13
% M
% Asn:
13
13
0
13
25
13
0
7
7
0
0
44
0
0
44
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
7
7
0
0
0
0
7
7
7
% Q
% Arg:
0
13
0
0
7
0
0
0
50
0
13
0
0
0
0
% R
% Ser:
7
0
0
0
0
7
0
50
0
0
0
7
7
0
0
% S
% Thr:
0
13
0
0
0
0
7
13
7
0
7
7
0
0
7
% T
% Val:
0
7
0
7
0
0
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
44
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _