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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCB
All Species:
32.42
Human Site:
T111
Identified Species:
47.56
UniProt:
O75439
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75439
NP_004270.2
489
54366
T111
E
H
M
A
F
K
G
T
K
K
R
S
Q
L
D
Chimpanzee
Pan troglodytes
XP_001160333
489
54373
T111
E
H
M
A
F
K
G
T
K
K
R
S
Q
L
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533104
513
56776
T135
E
H
M
A
F
K
G
T
K
K
R
S
Q
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXT8
489
54596
T111
E
H
M
A
F
K
G
T
K
K
R
S
Q
L
D
Rat
Rattus norvegicus
Q03346
489
54247
T111
E
H
M
A
F
K
G
T
K
K
R
S
Q
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507859
495
54657
T117
E
H
M
A
F
K
G
T
K
K
R
S
Q
L
D
Chicken
Gallus gallus
XP_415962
487
54047
T108
E
H
M
A
F
K
G
T
K
K
R
S
Q
L
D
Frog
Xenopus laevis
NP_001085137
479
53355
D110
T
K
N
R
S
Q
L
D
L
E
L
E
I
E
N
Zebra Danio
Brachydanio rerio
NP_001012514
470
52313
E108
S
Q
L
D
L
E
L
E
I
E
N
M
G
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650401
470
51856
N108
D
L
E
L
E
V
E
N
L
G
A
H
L
N
A
Honey Bee
Apis mellifera
XP_393509
477
53330
L108
R
S
Q
T
D
L
E
L
E
I
E
N
M
G
A
Nematode Worm
Caenorhab. elegans
P98080
471
51717
F113
I
G
A
K
L
N
S
F
T
E
R
D
Q
T
A
Sea Urchin
Strong. purpuratus
XP_001176813
476
53032
L108
R
T
Q
M
E
L
E
L
E
I
E
N
M
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42290
531
59141
T151
E
H
M
I
F
K
G
T
D
R
R
T
V
R
A
Baker's Yeast
Sacchar. cerevisiae
P10507
462
51065
T108
A
Y
T
S
R
E
N
T
V
Y
Y
A
K
S
L
Red Bread Mold
Neurospora crassa
P11913
476
52538
Y116
M
G
A
H
L
N
A
Y
T
S
R
E
N
T
V
Conservation
Percent
Protein Identity:
100
99.3
N.A.
87.5
N.A.
90.1
89.7
N.A.
82.8
81.8
82.6
77.9
N.A.
66
62.5
38
70.7
Protein Similarity:
100
99.3
N.A.
91.2
N.A.
94.8
95
N.A.
90
89.7
88.9
85
N.A.
76.2
77.5
59.9
84.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
0
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
20
20
N.A.
6.6
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.1
43.3
48.2
Protein Similarity:
N.A.
N.A.
N.A.
63.8
61.9
66.6
P-Site Identity:
N.A.
N.A.
N.A.
53.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
40
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
44
0
0
7
0
0
0
7
7
0
7
32
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
7
0
0
7
7
0
0
7
0
0
44
% D
% Glu:
50
0
7
0
13
13
19
7
13
19
13
13
0
7
0
% E
% Phe:
0
0
0
0
50
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
50
0
0
7
0
0
7
13
0
% G
% His:
0
50
0
7
0
0
0
0
0
0
0
7
0
0
7
% H
% Ile:
7
0
0
7
0
0
0
0
7
13
0
0
7
0
0
% I
% Lys:
0
7
0
7
0
50
0
0
44
44
0
0
7
0
0
% K
% Leu:
0
7
7
7
19
13
13
13
13
0
7
0
7
44
7
% L
% Met:
7
0
50
7
0
0
0
0
0
0
0
7
13
0
0
% M
% Asn:
0
0
7
0
0
13
7
7
0
0
7
13
7
7
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
13
0
0
7
0
0
0
0
0
0
50
0
0
% Q
% Arg:
13
0
0
7
7
0
0
0
0
7
63
0
0
7
0
% R
% Ser:
7
7
0
7
7
0
7
0
0
7
0
44
0
7
0
% S
% Thr:
7
7
7
7
0
0
0
57
13
0
0
7
0
13
0
% T
% Val:
0
0
0
0
0
7
0
0
7
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
7
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _