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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCB
All Species:
30.3
Human Site:
Y142
Identified Species:
44.44
UniProt:
O75439
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75439
NP_004270.2
489
54366
Y142
S
R
E
Q
T
V
Y
Y
A
K
A
F
S
K
D
Chimpanzee
Pan troglodytes
XP_001160333
489
54373
Y142
S
R
E
Q
T
V
Y
Y
A
K
A
F
S
K
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533104
513
56776
Y166
S
R
E
Q
T
V
Y
Y
A
K
A
F
S
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXT8
489
54596
Y142
S
R
E
Q
T
V
Y
Y
A
K
A
F
S
R
D
Rat
Rattus norvegicus
Q03346
489
54247
Y142
S
R
E
Q
T
V
Y
Y
A
K
A
F
S
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507859
495
54657
Y148
S
R
E
Q
T
V
Y
Y
A
K
A
F
S
R
D
Chicken
Gallus gallus
XP_415962
487
54047
Y139
S
R
E
Q
T
V
Y
Y
A
K
A
F
S
K
D
Frog
Xenopus laevis
NP_001085137
479
53355
F138
T
V
Y
Y
A
K
A
F
S
K
D
L
P
R
A
Zebra Danio
Brachydanio rerio
NP_001012514
470
52313
L136
A
K
A
F
S
K
D
L
P
R
A
V
E
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650401
470
51856
A136
L
S
K
D
V
P
K
A
V
E
I
L
A
D
I
Honey Bee
Apis mellifera
XP_393509
477
53330
D136
Y
A
K
C
L
A
E
D
V
P
K
A
V
E
I
Nematode Worm
Caenorhab. elegans
P98080
471
51717
L141
V
D
I
L
A
D
V
L
R
N
S
K
L
E
A
Sea Urchin
Strong. purpuratus
XP_001176813
476
53032
D136
Y
A
K
C
F
E
S
D
V
P
R
A
V
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42290
531
59141
Y182
S
R
E
Q
T
T
Y
Y
A
K
V
L
D
S
N
Baker's Yeast
Sacchar. cerevisiae
P10507
462
51065
D136
I
L
T
K
S
V
L
D
N
S
A
I
E
R
E
Red Bread Mold
Neurospora crassa
P11913
476
52538
Q145
D
I
L
Q
D
I
L
Q
N
S
K
L
E
E
S
Conservation
Percent
Protein Identity:
100
99.3
N.A.
87.5
N.A.
90.1
89.7
N.A.
82.8
81.8
82.6
77.9
N.A.
66
62.5
38
70.7
Protein Similarity:
100
99.3
N.A.
91.2
N.A.
94.8
95
N.A.
90
89.7
88.9
85
N.A.
76.2
77.5
59.9
84.2
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
93.3
100
6.6
6.6
N.A.
0
0
0
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
33.3
33.3
N.A.
20
13.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.1
43.3
48.2
Protein Similarity:
N.A.
N.A.
N.A.
63.8
61.9
66.6
P-Site Identity:
N.A.
N.A.
N.A.
60
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
7
0
13
7
7
7
50
0
57
13
7
0
13
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
7
7
7
19
0
0
7
0
7
7
44
% D
% Glu:
0
0
50
0
0
7
7
0
0
7
0
0
19
25
7
% E
% Phe:
0
0
0
7
7
0
0
7
0
0
0
44
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
7
0
0
7
0
0
0
0
7
7
0
7
19
% I
% Lys:
0
7
19
7
0
13
7
0
0
57
13
7
0
32
0
% K
% Leu:
7
7
7
7
7
0
13
13
0
0
0
25
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
7
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
7
0
0
7
13
0
0
7
0
0
% P
% Gln:
0
0
0
57
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
50
0
0
0
0
0
0
7
7
7
0
0
25
0
% R
% Ser:
50
7
0
0
13
0
7
0
7
13
7
0
44
7
7
% S
% Thr:
7
0
7
0
50
7
0
0
0
0
0
0
0
0
0
% T
% Val:
7
7
0
0
7
50
7
0
19
0
7
7
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
7
7
0
0
50
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _