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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCB
All Species:
11.21
Human Site:
Y36
Identified Species:
16.44
UniProt:
O75439
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75439
NP_004270.2
489
54366
Y36
G
A
A
G
R
S
L
Y
F
G
E
N
R
L
R
Chimpanzee
Pan troglodytes
XP_001160333
489
54373
Y36
G
A
A
G
R
S
L
Y
F
G
E
N
R
L
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533104
513
56776
C60
A
R
G
L
P
S
L
C
L
G
G
S
R
W
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXT8
489
54596
Y36
R
A
A
A
Q
P
L
Y
F
G
G
D
R
L
R
Rat
Rattus norvegicus
Q03346
489
54247
Y36
A
A
A
A
Q
P
L
Y
F
G
G
D
R
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507859
495
54657
N42
G
V
G
R
R
P
I
N
V
G
E
K
R
F
R
Chicken
Gallus gallus
XP_415962
487
54047
H33
G
S
G
N
R
C
V
H
V
G
K
G
R
F
R
Frog
Xenopus laevis
NP_001085137
479
53355
R35
G
F
G
I
S
R
N
R
S
T
Q
A
F
T
Q
Zebra Danio
Brachydanio rerio
NP_001012514
470
52313
A33
N
R
S
V
S
A
P
A
V
N
Q
V
V
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650401
470
51856
K33
K
S
A
A
T
L
Q
K
T
L
L
N
I
P
A
Honey Bee
Apis mellifera
XP_393509
477
53330
A33
K
Q
W
R
S
T
S
A
S
L
K
E
I
L
M
Nematode Worm
Caenorhab. elegans
P98080
471
51717
A38
V
L
A
S
A
P
Q
A
E
V
T
T
L
K
N
Sea Urchin
Strong. purpuratus
XP_001176813
476
53032
Q33
G
S
R
L
R
S
T
Q
T
A
S
E
T
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42290
531
59141
L76
E
N
P
D
K
R
F
L
K
Y
A
S
P
H
P
Baker's Yeast
Sacchar. cerevisiae
P10507
462
51065
N33
T
R
T
S
K
L
P
N
G
L
T
I
A
T
E
Red Bread Mold
Neurospora crassa
P11913
476
52538
Q41
S
G
T
G
I
K
T
Q
T
T
T
L
K
N
G
Conservation
Percent
Protein Identity:
100
99.3
N.A.
87.5
N.A.
90.1
89.7
N.A.
82.8
81.8
82.6
77.9
N.A.
66
62.5
38
70.7
Protein Similarity:
100
99.3
N.A.
91.2
N.A.
94.8
95
N.A.
90
89.7
88.9
85
N.A.
76.2
77.5
59.9
84.2
P-Site Identity:
100
100
N.A.
33.3
N.A.
60
60
N.A.
40
33.3
6.6
6.6
N.A.
13.3
6.6
6.6
26.6
P-Site Similarity:
100
100
N.A.
40
N.A.
73.3
73.3
N.A.
46.6
60
20
26.6
N.A.
20
20
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.1
43.3
48.2
Protein Similarity:
N.A.
N.A.
N.A.
63.8
61.9
66.6
P-Site Identity:
N.A.
N.A.
N.A.
0
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
25
38
19
7
7
0
19
0
7
7
7
7
0
7
% A
% Cys:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
13
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
7
0
19
13
0
0
7
% E
% Phe:
0
7
0
0
0
0
7
0
25
0
0
0
7
13
0
% F
% Gly:
38
7
25
19
0
0
0
0
7
44
19
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
7
7
0
7
0
0
0
0
7
13
0
0
% I
% Lys:
13
0
0
0
13
7
0
7
7
0
13
7
7
7
0
% K
% Leu:
0
7
0
13
0
13
32
7
7
19
7
7
7
44
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
7
0
7
0
0
7
13
0
7
0
19
0
7
13
% N
% Pro:
0
0
7
0
7
25
13
0
0
0
0
0
7
7
7
% P
% Gln:
0
7
0
0
13
0
13
13
0
0
13
0
0
0
7
% Q
% Arg:
7
19
7
13
32
13
0
7
0
0
0
0
44
0
44
% R
% Ser:
7
19
7
13
19
25
7
0
13
0
7
13
0
0
0
% S
% Thr:
7
0
13
0
7
7
13
0
19
13
19
7
7
13
0
% T
% Val:
7
7
0
7
0
0
7
0
19
7
0
7
7
0
7
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _