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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCB
All Species:
58.79
Human Site:
Y429
Identified Species:
86.22
UniProt:
O75439
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75439
NP_004270.2
489
54366
Y429
I
G
R
Q
M
L
C
Y
N
R
R
I
P
I
P
Chimpanzee
Pan troglodytes
XP_001160333
489
54373
Y429
I
G
R
Q
M
L
C
Y
N
R
R
I
P
I
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533104
513
56776
Y453
I
G
R
Q
M
L
C
Y
N
R
R
I
P
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXT8
489
54596
Y429
I
G
R
Q
M
L
C
Y
N
R
R
I
P
I
P
Rat
Rattus norvegicus
Q03346
489
54247
Y429
I
G
R
Q
M
L
C
Y
N
R
R
I
P
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507859
495
54657
Y435
I
G
R
Q
M
L
C
Y
N
R
R
I
P
I
P
Chicken
Gallus gallus
XP_415962
487
54047
Y427
I
G
R
Q
M
L
C
Y
K
R
R
I
P
I
P
Frog
Xenopus laevis
NP_001085137
479
53355
Y419
I
G
R
Q
M
L
C
Y
N
R
R
I
P
L
P
Zebra Danio
Brachydanio rerio
NP_001012514
470
52313
Y413
I
G
R
Q
M
L
C
Y
S
R
R
I
P
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650401
470
51856
Y410
I
G
R
Q
I
L
C
Y
N
R
R
I
P
L
H
Honey Bee
Apis mellifera
XP_393509
477
53330
Y417
I
G
R
Q
M
L
C
Y
N
R
R
I
P
L
H
Nematode Worm
Caenorhab. elegans
P98080
471
51717
T411
N
A
K
E
L
L
Y
T
G
N
L
R
Q
L
S
Sea Urchin
Strong. purpuratus
XP_001176813
476
53032
Y416
I
G
R
Q
M
L
C
Y
G
R
R
I
P
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42290
531
59141
Y471
I
G
R
Q
L
L
T
Y
G
R
R
I
P
T
A
Baker's Yeast
Sacchar. cerevisiae
P10507
462
51065
T405
I
G
R
Q
V
V
T
T
G
K
R
L
S
P
E
Red Bread Mold
Neurospora crassa
P11913
476
52538
T416
I
G
R
Q
I
V
T
T
G
R
R
M
S
P
A
Conservation
Percent
Protein Identity:
100
99.3
N.A.
87.5
N.A.
90.1
89.7
N.A.
82.8
81.8
82.6
77.9
N.A.
66
62.5
38
70.7
Protein Similarity:
100
99.3
N.A.
91.2
N.A.
94.8
95
N.A.
90
89.7
88.9
85
N.A.
76.2
77.5
59.9
84.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
93.3
93.3
80
N.A.
80
86.6
6.6
86.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
93.3
93.3
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.1
43.3
48.2
Protein Similarity:
N.A.
N.A.
N.A.
63.8
61.9
66.6
P-Site Identity:
N.A.
N.A.
N.A.
66.6
33.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
60
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
94
0
0
0
0
0
0
32
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% H
% Ile:
94
0
0
0
13
0
0
0
0
0
0
82
0
44
0
% I
% Lys:
0
0
7
0
0
0
0
0
7
7
0
0
0
0
0
% K
% Leu:
0
0
0
0
13
88
0
0
0
0
7
7
0
38
0
% L
% Met:
0
0
0
0
69
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
57
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
82
13
57
% P
% Gln:
0
0
0
94
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
94
0
0
0
0
0
0
88
94
7
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
7
0
0
0
13
0
7
% S
% Thr:
0
0
0
0
0
0
19
19
0
0
0
0
0
7
0
% T
% Val:
0
0
0
0
7
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _