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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAF
All Species:
11.82
Human Site:
S149
Identified Species:
32.5
UniProt:
O75444
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75444
NP_001026974.1
373
38492
S149
A
G
A
G
A
G
A
S
L
G
G
S
G
E
E
Chimpanzee
Pan troglodytes
XP_525325
233
25698
P36
L
G
G
A
V
A
Q
P
L
P
E
A
G
G
W
Rhesus Macaque
Macaca mulatta
XP_001101624
258
28799
S61
Q
P
L
Q
S
F
D
S
F
R
G
A
H
H
H
Dog
Lupus familis
XP_542997
325
35521
I128
R
R
G
L
P
K
G
I
P
G
F
V
N
H
H
Cat
Felis silvestris
Mouse
Mus musculus
P54843
370
38417
S149
A
G
A
G
A
G
A
S
L
G
G
S
G
E
E
Rat
Rattus norvegicus
P54844
369
38439
S149
A
G
A
G
A
G
A
S
L
G
G
S
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90888
311
35449
S114
A
V
E
A
L
I
G
S
H
Q
V
S
Q
Q
L
Frog
Xenopus laevis
Q6DE84
313
35730
Q116
A
V
E
A
L
I
G
Q
H
Q
M
P
P
Q
L
Zebra Danio
Brachydanio rerio
Q98UK4
327
35806
Y130
Q
L
Q
S
F
D
G
Y
A
R
G
Q
Q
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37
43.1
39.4
N.A.
97.3
96.5
N.A.
N.A.
53
51.7
78
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
45.3
50.1
49.3
N.A.
98.1
97
N.A.
N.A.
61.9
60.3
81.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
13.3
6.6
N.A.
100
100
N.A.
N.A.
20
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
6.6
N.A.
100
100
N.A.
N.A.
26.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
56
0
34
34
34
12
34
0
12
0
0
23
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
23
0
0
0
0
0
0
0
12
0
0
34
34
% E
% Phe:
0
0
0
0
12
12
0
0
12
0
12
0
0
12
0
% F
% Gly:
0
45
23
34
0
34
45
0
0
45
56
0
45
12
12
% G
% His:
0
0
0
0
0
0
0
0
23
0
0
0
12
23
23
% H
% Ile:
0
0
0
0
0
23
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
12
12
12
23
0
0
0
45
0
0
0
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
12
0
0
12
0
0
12
12
12
0
12
12
0
0
% P
% Gln:
23
0
12
12
0
0
12
12
0
23
0
12
23
23
0
% Q
% Arg:
12
12
0
0
0
0
0
0
0
23
0
0
0
0
0
% R
% Ser:
0
0
0
12
12
0
0
56
0
0
0
45
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
23
0
0
12
0
0
0
0
0
12
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _