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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USH2A All Species: 20.3
Human Site: S5087 Identified Species: 63.81
UniProt: O75445 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75445 NP_009054.5 5202 575600 S5087 V P L Q K R M S P L N V Y P P
Chimpanzee Pan troglodytes XP_514197 5202 575326 S5087 V P L Q K R M S P L N V Y P P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545710 5199 571771 S5084 V P I Q K R M S P L N V Y P P
Cat Felis silvestris
Mouse Mus musculus Q2QI47 5193 569698 T5078 V P L Q K R M T P L S V Y P P
Rat Rattus norvegicus Q8K3K1 1512 167574 R1398 K I S M V S E R S P Q R D V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419417 5229 576609 S5110 V P L Q K R T S P M S V Y S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697435 5334 582391 T5207 M P L Q R R S T K Y P P K D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793438 5055 546449 S4940 K A H N F T F S S M L P R Y P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 N.A. 83.9 N.A. 71.2 20.9 N.A. N.A. 66.3 N.A. 51.3 N.A. N.A. N.A. N.A. 40
Protein Similarity: 100 99.1 N.A. 90.4 N.A. 82.8 24.7 N.A. N.A. 79.3 N.A. 68.3 N.A. N.A. N.A. N.A. 57.5
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 6.6 N.A. N.A. 66.6 N.A. 26.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 6.6 N.A. N.A. 80 N.A. 46.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 13 13 0 % D
% Glu: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 13 0 13 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 25 0 0 0 63 0 0 0 13 0 0 0 13 0 0 % K
% Leu: 0 0 63 0 0 0 0 0 0 50 13 0 0 0 0 % L
% Met: 13 0 0 13 0 0 50 0 0 25 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 38 0 0 0 0 % N
% Pro: 0 75 0 0 0 0 0 0 63 13 13 25 0 50 75 % P
% Gln: 0 0 0 75 0 0 0 0 0 0 13 0 0 0 0 % Q
% Arg: 0 0 0 0 13 75 0 13 0 0 0 13 13 0 0 % R
% Ser: 0 0 13 0 0 13 13 63 25 0 25 0 0 13 13 % S
% Thr: 0 0 0 0 0 13 13 25 0 0 0 0 0 0 13 % T
% Val: 63 0 0 0 13 0 0 0 0 0 0 63 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 13 0 0 63 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _