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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USH2A All Species: 18.48
Human Site: S5146 Identified Species: 58.1
UniProt: O75445 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75445 NP_009054.5 5202 575600 S5146 G S L H R S V S Q L M D I Q D
Chimpanzee Pan troglodytes XP_514197 5202 575326 S5146 G S L H R S V S Q L M D I Q D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545710 5199 571771 S5143 G S L H C S V S Q L M D L Q D
Cat Felis silvestris
Mouse Mus musculus Q2QI47 5193 569698 S5137 S S L H R S V S Q L M D M A D
Rat Rattus norvegicus Q8K3K1 1512 167574 T1457 L G E G Q T L T A G K N V L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419417 5229 576609 S5169 A S L H R S V S Q L L D I Y D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697435 5334 582391 Q5266 S V L R V P S Q S Q L S H A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793438 5055 546449 L4999 E V M D K N S L K Y L D E D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 N.A. 83.9 N.A. 71.2 20.9 N.A. N.A. 66.3 N.A. 51.3 N.A. N.A. N.A. N.A. 40
Protein Similarity: 100 99.1 N.A. 90.4 N.A. 82.8 24.7 N.A. N.A. 79.3 N.A. 68.3 N.A. N.A. N.A. N.A. 57.5
P-Site Identity: 100 100 N.A. 86.6 N.A. 80 0 N.A. N.A. 80 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 86.6 40 N.A. N.A. 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 0 0 0 13 0 0 0 0 25 0 % A
% Cys: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 13 0 0 0 0 0 0 0 75 0 13 75 % D
% Glu: 13 0 13 0 0 0 0 0 0 0 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 38 13 0 13 0 0 0 0 0 13 0 0 0 0 0 % G
% His: 0 0 0 63 0 0 0 0 0 0 0 0 13 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 38 0 0 % I
% Lys: 0 0 0 0 13 0 0 0 13 0 13 0 0 0 0 % K
% Leu: 13 0 75 0 0 0 13 13 0 63 38 0 13 13 0 % L
% Met: 0 0 13 0 0 0 0 0 0 0 50 0 13 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 0 13 0 0 0 % N
% Pro: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 0 0 13 63 13 0 0 0 38 0 % Q
% Arg: 0 0 0 13 50 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 25 63 0 0 0 63 25 63 13 0 0 13 0 0 0 % S
% Thr: 0 0 0 0 0 13 0 13 0 0 0 0 0 0 13 % T
% Val: 0 25 0 0 13 0 63 0 0 0 0 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 13 0 0 0 13 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _