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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USH2A
All Species:
22.12
Human Site:
T2449
Identified Species:
69.52
UniProt:
O75445
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75445
NP_009054.5
5202
575600
T2449
R
L
S
S
A
T
P
T
S
L
Q
V
V
W
S
Chimpanzee
Pan troglodytes
XP_514197
5202
575326
T2449
R
L
S
S
A
T
P
T
S
L
Q
V
V
W
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545710
5199
571771
T2447
R
L
S
S
A
T
P
T
S
L
Q
V
V
W
S
Cat
Felis silvestris
Mouse
Mus musculus
Q2QI47
5193
569698
T2440
R
L
A
A
A
A
P
T
S
L
Q
V
V
W
S
Rat
Rattus norvegicus
Q8K3K1
1512
167574
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419417
5229
576609
T2468
R
L
S
S
A
T
P
T
S
L
Q
V
V
W
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697435
5334
582391
T2519
R
L
A
A
A
T
P
T
S
L
Q
V
S
W
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793438
5055
546449
I2368
N
E
Y
E
F
R
V
I
A
I
N
N
A
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
83.9
N.A.
71.2
20.9
N.A.
N.A.
66.3
N.A.
51.3
N.A.
N.A.
N.A.
N.A.
40
Protein Similarity:
100
99.1
N.A.
90.4
N.A.
82.8
24.7
N.A.
N.A.
79.3
N.A.
68.3
N.A.
N.A.
N.A.
N.A.
57.5
P-Site Identity:
100
100
N.A.
100
N.A.
80
0
N.A.
N.A.
100
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
0
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
25
75
13
0
0
13
0
0
0
13
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
0
13
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
75
0
0
0
0
0
0
0
75
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
13
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
13
% Q
% Arg:
75
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
50
50
0
0
0
0
75
0
0
0
13
0
63
% S
% Thr:
0
0
0
0
0
63
0
75
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
13
0
0
0
0
75
63
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% W
% Tyr:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _