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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USH2A All Species: 17.88
Human Site: T5111 Identified Species: 56.19
UniProt: O75445 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75445 NP_009054.5 5202 575600 T5111 T K I P R S G T P V S I R S N
Chimpanzee Pan troglodytes XP_514197 5202 575326 T5111 T K I P R S G T P V S I R S N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545710 5199 571771 T5108 T K I P H S G T P V S I R S N
Cat Felis silvestris
Mouse Mus musculus Q2QI47 5193 569698 T5102 T R L P R S G T P M S I R S S
Rat Rattus norvegicus Q8K3K1 1512 167574 Y1422 A E S Q D Q S Y I V Q R L K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419417 5229 576609 S5134 T K I P G V G S P T S S R G I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697435 5334 582391 R5231 S C S I T L K R F A M R T E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793438 5055 546449 S4964 P Q A I S R Q S S M H S L H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 N.A. 83.9 N.A. 71.2 20.9 N.A. N.A. 66.3 N.A. 51.3 N.A. N.A. N.A. N.A. 40
Protein Similarity: 100 99.1 N.A. 90.4 N.A. 82.8 24.7 N.A. N.A. 79.3 N.A. 68.3 N.A. N.A. N.A. N.A. 57.5
P-Site Identity: 100 100 N.A. 93.3 N.A. 73.3 6.6 N.A. N.A. 53.3 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 13.3 N.A. N.A. 60 N.A. 6.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 13 0 0 0 0 0 0 13 0 0 0 0 0 % A
% Cys: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 13 0 0 0 0 0 0 0 0 0 0 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 13 0 63 0 0 0 0 0 0 13 13 % G
% His: 0 0 0 0 13 0 0 0 0 0 13 0 0 13 0 % H
% Ile: 0 0 50 25 0 0 0 0 13 0 0 50 0 0 13 % I
% Lys: 0 50 0 0 0 0 13 0 0 0 0 0 0 13 0 % K
% Leu: 0 0 13 0 0 13 0 0 0 0 0 0 25 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 25 13 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % N
% Pro: 13 0 0 63 0 0 0 0 63 0 0 0 0 0 13 % P
% Gln: 0 13 0 13 0 13 13 0 0 0 13 0 0 0 0 % Q
% Arg: 0 13 0 0 38 13 0 13 0 0 0 25 63 0 0 % R
% Ser: 13 0 25 0 13 50 13 25 13 0 63 25 0 50 13 % S
% Thr: 63 0 0 0 13 0 0 50 0 13 0 0 13 0 0 % T
% Val: 0 0 0 0 0 13 0 0 0 50 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _