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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED24
All Species:
30.91
Human Site:
T683
Identified Species:
61.82
UniProt:
O75448
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75448
NP_001072986.1
989
110305
T683
D
V
L
Q
Q
T
A
T
Q
I
K
F
P
S
T
Chimpanzee
Pan troglodytes
XP_001171021
1014
112994
T708
D
V
L
Q
Q
T
A
T
Q
I
K
F
P
S
T
Rhesus Macaque
Macaca mulatta
XP_001087996
1063
118362
T757
D
V
L
Q
Q
T
A
T
Q
I
K
F
P
S
T
Dog
Lupus familis
XP_851230
989
110079
T683
D
V
L
Q
Q
T
A
T
Q
I
K
F
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99K74
987
109966
T681
D
V
L
Q
Q
T
A
T
Q
I
K
F
P
S
T
Rat
Rattus norvegicus
Q4V8B3
987
110063
T681
D
V
L
Q
Q
T
A
T
Q
I
K
F
P
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512944
587
64800
G299
I
W
K
A
C
F
V
G
L
I
E
S
P
E
G
Chicken
Gallus gallus
Q5F3M0
986
110826
T680
D
V
L
Q
Q
T
A
T
Q
I
K
F
P
S
T
Frog
Xenopus laevis
Q6PI53
988
110495
T681
E
V
L
Q
Q
T
T
T
Q
I
K
F
S
A
A
Zebra Danio
Brachydanio rerio
Q2PW47
989
110843
L682
D
V
F
Q
Q
T
G
L
S
L
R
P
A
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSF2
993
111724
I672
R
L
A
L
S
Y
Q
I
I
R
K
M
Q
H
D
Honey Bee
Apis mellifera
XP_392006
991
111259
D680
I
I
R
K
M
Q
Y
D
V
H
P
P
T
Q
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
92.1
96.1
N.A.
94.2
94.5
N.A.
46.4
86.5
76.6
76.1
N.A.
29.2
34
N.A.
N.A.
Protein Similarity:
100
97.5
92.4
98
N.A.
97.1
97.1
N.A.
51.5
92.4
87.6
85
N.A.
50.8
56
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
66.6
33.3
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
80
46.6
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
59
0
0
0
0
0
9
9
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
9
0
0
9
9
% E
% Phe:
0
0
9
0
0
9
0
0
0
0
0
67
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% H
% Ile:
17
9
0
0
0
0
0
9
9
75
0
0
0
0
0
% I
% Lys:
0
0
9
9
0
0
0
0
0
0
75
0
0
0
0
% K
% Leu:
0
9
67
9
0
0
0
9
9
9
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
17
67
0
0
% P
% Gln:
0
0
0
75
75
9
9
0
67
0
0
0
9
9
0
% Q
% Arg:
9
0
9
0
0
0
0
0
0
9
9
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
0
9
0
0
9
9
59
9
% S
% Thr:
0
0
0
0
0
75
9
67
0
0
0
0
9
0
59
% T
% Val:
0
75
0
0
0
0
9
0
9
0
0
0
0
9
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _