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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KATNA1 All Species: 34.55
Human Site: S470 Identified Species: 54.29
UniProt: O75449 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75449 NP_008975.1 491 55965 S470 E M A L K K V S K S V S A A D
Chimpanzee Pan troglodytes XP_001173237 491 55916 S470 E M A L K K V S K S V S A A D
Rhesus Macaque Macaca mulatta XP_001086813 396 44879 K376 M A L K K V S K S V S A A D I
Dog Lupus familis XP_533445 491 55924 S470 E M A L K K V S K S V S A A D
Cat Felis silvestris
Mouse Mus musculus Q9WV86 491 55931 S470 E M A L K K I S K S V S A A D
Rat Rattus norvegicus Q6E0V2 491 55825 S470 E M A L K K V S K S V S A A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506598 493 55773 S472 G M A L K K V S K S V S A A D
Chicken Gallus gallus Q1HGK7 492 56020 S471 E I A L K K V S K S V S A A D
Frog Xenopus laevis Q9PUL2 486 55412 K465 D F E M A L K K V S K S V S A
Zebra Danio Brachydanio rerio Q5RII9 485 54863 S464 E T A L K K V S K S V S A A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397402 506 57695 N485 D E A V E R C N K S V S Q E D
Nematode Worm Caenorhab. elegans P34808 472 51721 V450 F E A A L Q A V S P S A G P D
Sea Urchin Strong. purpuratus O61577 516 57575 S495 L L A L Q K V S K S V G K E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 V501 F E E A I R K V Q P S V S S S
Baker's Yeast Sacchar. cerevisiae P52917 437 48154 R414 L K A I K S T R P T V N E D D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 78.6 97.3 N.A. 93 93.4 N.A. 91 88.6 84.5 77.1 N.A. N.A. 56.5 34.4 60.6
Protein Similarity: 100 99.8 79.8 98.7 N.A. 95.9 96.7 N.A. 94.9 94.5 91 85.7 N.A. N.A. 71.9 53.3 74
P-Site Identity: 100 100 13.3 100 N.A. 93.3 100 N.A. 93.3 93.3 13.3 93.3 N.A. N.A. 40 13.3 60
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 93.3 100 33.3 93.3 N.A. N.A. 73.3 26.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 49.3 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 65.7 54.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 80 14 7 0 7 0 0 0 0 14 60 54 7 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 0 0 0 0 0 0 0 0 0 0 14 80 % D
% Glu: 47 20 14 0 7 0 0 0 0 0 0 0 7 14 0 % E
% Phe: 14 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 7 0 7 0 0 0 0 0 0 0 7 % I
% Lys: 0 7 0 7 67 60 14 14 67 0 7 0 7 0 0 % K
% Leu: 14 7 7 60 7 7 0 0 0 0 0 0 0 0 0 % L
% Met: 7 40 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 14 0 0 0 7 0 % P
% Gln: 0 0 0 0 7 7 0 0 7 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 0 14 0 7 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 7 7 60 14 74 20 67 7 14 7 % S
% Thr: 0 7 0 0 0 0 7 0 0 7 0 0 0 0 0 % T
% Val: 0 0 0 7 0 7 54 14 7 7 74 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _