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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KATNA1 All Species: 34.85
Human Site: T185 Identified Species: 54.76
UniProt: O75449 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75449 NP_008975.1 491 55965 T185 E T N K F D S T G Y D K D L V
Chimpanzee Pan troglodytes XP_001173237 491 55916 T185 E T N K F D S T G Y D K D L V
Rhesus Macaque Macaca mulatta XP_001086813 396 44879 M134 K E A V V L P M W M P E F F K
Dog Lupus familis XP_533445 491 55924 T185 E T S K F D S T G Y D K D L V
Cat Felis silvestris
Mouse Mus musculus Q9WV86 491 55931 T185 E A N K F D G T G Y D K D L V
Rat Rattus norvegicus Q6E0V2 491 55825 T185 E A N K F D S T G Y D K D L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506598 493 55773 T187 E I H K F D G T G Y D K D L V
Chicken Gallus gallus Q1HGK7 492 56020 T186 E P K K F D S T G Y D K D L V
Frog Xenopus laevis Q9PUL2 486 55412 S182 E V K R F D G S G Y D K D L I
Zebra Danio Brachydanio rerio Q5RII9 485 54863 G180 E V K R F D R G G E D K D L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397402 506 57695 S202 E E R K F E P S G N D R D L V
Nematode Worm Caenorhab. elegans P34808 472 51721 S168 A G D S F D A S A Y D A Y I V
Sea Urchin Strong. purpuratus O61577 516 57575 A210 D E K K F D P A G Y D K D L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 E215 K S K R G L Y E G P D E D L A
Baker's Yeast Sacchar. cerevisiae P52917 437 48154 N162 F P H L F K G N R K P T S G I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 78.6 97.3 N.A. 93 93.4 N.A. 91 88.6 84.5 77.1 N.A. N.A. 56.5 34.4 60.6
Protein Similarity: 100 99.8 79.8 98.7 N.A. 95.9 96.7 N.A. 94.9 94.5 91 85.7 N.A. N.A. 71.9 53.3 74
P-Site Identity: 100 100 0 93.3 N.A. 86.6 93.3 N.A. 80 86.6 60 53.3 N.A. N.A. 53.3 33.3 66.6
P-Site Similarity: 100 100 13.3 100 N.A. 86.6 93.3 N.A. 86.6 86.6 80 66.6 N.A. N.A. 73.3 60 73.3
Percent
Protein Identity: N.A. N.A. N.A. 49.3 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 65.7 54.3 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 7 0 0 0 7 7 7 0 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 74 0 0 0 0 87 0 80 0 0 % D
% Glu: 67 20 0 0 0 7 0 7 0 7 0 14 0 0 0 % E
% Phe: 7 0 0 0 87 0 0 0 0 0 0 0 7 7 0 % F
% Gly: 0 7 0 0 7 0 27 7 80 0 0 0 0 7 0 % G
% His: 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 20 % I
% Lys: 14 0 34 60 0 7 0 0 0 7 0 67 0 0 7 % K
% Leu: 0 0 0 7 0 14 0 0 0 0 0 0 0 80 0 % L
% Met: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % M
% Asn: 0 0 27 0 0 0 0 7 0 7 0 0 0 0 0 % N
% Pro: 0 14 0 0 0 0 20 0 0 7 14 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 20 0 0 7 0 7 0 0 7 0 0 0 % R
% Ser: 0 7 7 7 0 0 34 20 0 0 0 0 7 0 0 % S
% Thr: 0 20 0 0 0 0 0 47 0 0 0 7 0 0 0 % T
% Val: 0 14 0 7 7 0 0 0 0 0 0 0 0 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 67 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _