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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDH16
All Species:
10
Human Site:
S222
Identified Species:
27.5
UniProt:
O75452
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75452
NP_003699.3
317
35673
S222
S
K
E
R
F
L
K
S
F
L
E
I
W
D
R
Chimpanzee
Pan troglodytes
Q1WNP0
328
34870
N233
V
F
R
E
A
A
Q
N
P
E
E
V
A
E
V
Rhesus Macaque
Macaca mulatta
XP_001115484
317
35388
S222
S
K
E
R
F
L
K
S
F
L
E
I
W
D
R
Dog
Lupus familis
XP_531641
317
35841
G222
N
P
E
K
I
S
R
G
F
Q
E
T
W
D
R
Cat
Felis silvestris
Mouse
Mus musculus
O88451
316
35642
S221
N
Y
E
R
L
S
H
S
I
E
K
L
W
D
Q
Rat
Rattus norvegicus
P55006
317
35718
N222
N
M
E
R
L
S
D
N
L
K
K
L
W
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJZ5
339
38218
S245
I
A
V
T
N
L
Y
S
P
E
R
I
K
A
I
Frog
Xenopus laevis
Q0IH28
323
35135
T226
V
N
P
G
Y
I
K
T
N
L
S
L
N
A
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
F173
S
I
Y
C
A
S
K
F
A
V
G
A
F
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.7
94.3
76.9
N.A.
72.5
72.2
N.A.
N.A.
33.6
24.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.4
96.8
86.7
N.A.
84.5
84.8
N.A.
N.A.
49.8
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
40
N.A.
33.3
26.6
N.A.
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
60
N.A.
60
60
N.A.
N.A.
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
23
12
0
0
12
0
0
12
12
23
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
0
56
12
% D
% Glu:
0
0
56
12
0
0
0
0
0
34
45
0
0
12
0
% E
% Phe:
0
12
0
0
23
0
0
12
34
0
0
0
12
0
0
% F
% Gly:
0
0
0
12
0
0
0
12
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
0
12
12
0
0
12
0
0
34
0
0
12
% I
% Lys:
0
23
0
12
0
0
45
0
0
12
23
0
12
0
0
% K
% Leu:
0
0
0
0
23
34
0
0
12
34
0
34
0
0
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
12
0
0
12
0
0
23
12
0
0
0
12
0
0
% N
% Pro:
0
12
12
0
0
0
0
0
23
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
23
% Q
% Arg:
0
0
12
45
0
0
12
0
0
0
12
0
0
0
34
% R
% Ser:
34
0
0
0
0
45
0
45
0
0
12
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
12
0
0
0
12
0
12
0
% T
% Val:
23
0
12
0
0
0
0
0
0
12
0
12
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
56
0
0
% W
% Tyr:
0
12
12
0
12
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _