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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
19.09
Human Site:
S111
Identified Species:
32.31
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
S111
V
Q
A
S
P
C
R
S
S
D
G
I
L
Y
M
Chimpanzee
Pan troglodytes
XP_511585
968
108684
P108
W
I
Q
N
Y
A
S
P
V
V
A
F
Y
V
W
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
S204
V
Q
A
S
P
C
R
S
S
D
G
I
L
Y
M
Dog
Lupus familis
XP_853409
975
109686
S111
V
Q
A
S
P
C
R
S
S
D
G
I
L
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
S113
V
Q
A
S
P
C
R
S
S
D
G
I
L
Y
M
Rat
Rattus norvegicus
XP_573211
965
109012
K111
G
I
L
Y
M
G
K
K
Q
D
I
W
Y
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
S109
E
K
Q
Q
T
L
S
S
A
F
A
E
S
L
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
S116
V
Q
S
S
P
C
R
S
S
D
G
I
L
Y
T
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
G109
S
P
C
R
S
S
D
G
V
L
Y
T
G
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
L110
R
D
G
S
I
Y
Q
L
G
Q
M
G
S
L
K
Honey Bee
Apis mellifera
XP_392044
968
110555
Y109
D
P
K
D
G
S
L
Y
V
F
G
T
E
T
E
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
D123
A
S
P
C
K
G
N
D
G
I
L
Y
A
G
S
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
G133
V
S
S
S
P
F
R
G
P
D
N
M
L
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
N111
I
S
V
P
Y
L
E
N
R
S
L
N
E
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
6.6
N.A.
86.6
0
N.A.
6.6
6.6
0
46.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
20
N.A.
20
N.A.
93.3
0
N.A.
13.3
6.6
0
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
29
0
0
8
0
0
8
0
15
0
8
0
0
% A
% Cys:
0
0
8
8
0
36
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
0
8
0
0
8
8
0
50
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
8
0
0
0
0
8
15
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
15
0
8
0
0
0
% F
% Gly:
8
0
8
0
8
15
0
15
15
0
43
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
15
0
0
8
0
0
0
0
8
8
36
0
0
8
% I
% Lys:
0
8
8
0
8
0
8
8
0
0
0
0
0
8
15
% K
% Leu:
0
0
8
0
0
15
8
8
0
8
15
0
43
22
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
29
% M
% Asn:
0
0
0
8
0
0
8
8
0
0
8
8
0
0
0
% N
% Pro:
0
15
8
8
43
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
36
15
8
0
0
8
0
8
8
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
43
0
8
0
0
0
0
0
0
% R
% Ser:
8
22
15
50
8
15
15
43
36
8
0
0
15
0
15
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
15
0
8
15
% T
% Val:
43
0
8
0
0
0
0
0
22
8
0
0
0
15
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
8
15
8
0
8
0
0
8
8
15
43
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _