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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
4.85
Human Site:
S348
Identified Species:
8.21
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
S348
K
F
D
P
G
L
K
S
K
N
K
L
N
Y
L
Chimpanzee
Pan troglodytes
XP_511585
968
108684
H352
I
T
Y
P
L
S
M
H
Q
Q
Q
Q
L
Q
H
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
S441
K
F
D
S
G
L
K
S
K
N
K
L
N
Y
L
Dog
Lupus familis
XP_853409
975
109686
G348
K
F
D
P
G
L
K
G
K
N
K
L
N
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
G350
K
F
D
P
G
L
K
G
K
S
K
L
N
Y
L
Rat
Rattus norvegicus
XP_573211
965
109012
L345
G
K
S
K
L
N
Y
L
R
N
Y
W
L
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
I343
P
L
S
A
S
T
K
I
L
E
R
F
P
N
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
I353
R
Y
P
Q
G
S
V
I
S
A
H
Q
W
L
L
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
P342
P
S
T
D
V
K
Y
P
P
G
S
S
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
G344
K
L
L
D
G
P
T
G
D
Q
N
S
N
Q
E
Honey Bee
Apis mellifera
XP_392044
968
110555
N343
S
V
P
Q
L
G
K
N
D
N
G
N
V
P
L
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
I356
L
P
P
R
R
P
I
I
R
N
I
P
P
S
I
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
I368
G
T
N
I
Q
G
L
I
L
L
G
Y
H
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
S348
F
R
I
A
R
W
V
S
P
T
F
P
G
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
6.6
93.3
93.3
N.A.
86.6
6.6
N.A.
6.6
N.A.
13.3
6.6
N.A.
20
20
6.6
6.6
P-Site Similarity:
100
20
93.3
93.3
N.A.
93.3
20
N.A.
13.3
N.A.
26.6
13.3
N.A.
20
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
29
15
0
0
0
0
15
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% E
% Phe:
8
29
0
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
15
0
0
0
43
15
0
22
0
8
15
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
8
0
8
% H
% Ile:
8
0
8
8
0
0
8
29
0
0
8
0
0
8
22
% I
% Lys:
36
8
0
8
0
8
43
0
29
0
29
0
0
0
0
% K
% Leu:
8
15
8
0
22
29
8
8
15
8
0
29
15
15
58
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
8
0
43
8
8
36
8
0
% N
% Pro:
15
8
22
29
0
15
0
8
15
0
0
15
15
8
0
% P
% Gln:
0
0
0
15
8
0
0
0
8
15
8
15
0
15
0
% Q
% Arg:
8
8
0
8
15
0
0
0
15
0
8
0
0
0
0
% R
% Ser:
8
8
15
8
8
15
0
22
8
8
8
15
8
15
8
% S
% Thr:
0
15
8
0
0
8
8
0
0
8
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
15
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
0
% W
% Tyr:
0
8
8
0
0
0
15
0
0
0
8
8
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _