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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
18.79
Human Site:
S46
Identified Species:
31.79
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
S46
D
G
S
L
H
A
V
S
K
R
T
G
S
I
K
Chimpanzee
Pan troglodytes
XP_511585
968
108684
E43
L
L
Y
L
G
R
T
E
Y
T
I
T
M
Y
D
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
S139
D
G
S
L
H
A
V
S
K
R
T
G
S
I
K
Dog
Lupus familis
XP_853409
975
109686
S46
D
G
S
L
H
A
V
S
K
R
T
G
S
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
S48
D
G
S
L
H
A
V
S
K
R
T
G
S
I
K
Rat
Rattus norvegicus
XP_573211
965
109012
L46
T
G
S
I
K
W
T
L
K
E
D
P
V
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
D44
E
Q
P
A
F
L
P
D
P
N
D
G
S
L
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
S51
D
G
N
L
H
A
V
S
K
R
S
G
N
V
L
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
T44
L
H
A
V
S
K
Q
T
G
D
I
K
W
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
C45
G
E
D
E
K
T
D
C
T
D
L
A
R
D
E
Honey Bee
Apis mellifera
XP_392044
968
110555
D44
R
Q
Y
K
Q
K
R
D
T
E
L
I
S
E
Q
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
D58
D
G
R
L
R
A
L
D
S
E
T
G
E
I
K
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
N68
D
G
S
M
H
A
L
N
Q
R
T
G
R
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
K46
E
D
E
V
A
S
T
K
K
L
N
F
N
Y
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
6.6
100
100
N.A.
100
20
N.A.
13.3
N.A.
66.6
0
N.A.
0
6.6
53.3
53.3
P-Site Similarity:
100
6.6
100
100
N.A.
100
40
N.A.
26.6
N.A.
93.3
20
N.A.
6.6
13.3
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
50
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
50
8
8
0
0
0
8
22
0
15
15
0
0
8
8
% D
% Glu:
15
8
8
8
0
0
0
8
0
22
0
0
8
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
58
0
0
8
0
0
0
8
0
0
58
0
0
8
% G
% His:
0
8
0
0
43
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
15
8
0
36
8
% I
% Lys:
0
0
0
8
15
15
0
8
50
0
0
8
0
0
36
% K
% Leu:
15
8
0
50
0
8
15
8
0
8
15
0
0
15
15
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
8
8
0
15
0
0
% N
% Pro:
0
0
8
0
0
0
8
0
8
0
0
8
0
0
0
% P
% Gln:
0
15
0
0
8
0
8
0
8
0
0
0
0
0
15
% Q
% Arg:
8
0
8
0
8
8
8
0
0
43
0
0
15
0
0
% R
% Ser:
0
0
43
0
8
8
0
36
8
0
8
0
43
0
0
% S
% Thr:
8
0
0
0
0
8
22
8
15
8
43
8
0
15
0
% T
% Val:
0
0
0
15
0
0
36
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
15
0
0
0
0
0
8
0
0
0
0
15
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _