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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
38.18
Human Site:
S697
Identified Species:
64.62
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
S697
K
P
H
N
I
L
I
S
M
P
N
A
H
G
K
Chimpanzee
Pan troglodytes
XP_511585
968
108684
P682
G
T
E
G
W
I
A
P
E
M
L
S
E
D
C
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
S790
K
P
H
N
I
L
I
S
M
P
N
A
H
G
K
Dog
Lupus familis
XP_853409
975
109686
S695
K
P
H
N
I
L
L
S
M
P
N
A
H
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
S697
K
P
H
N
I
L
L
S
M
P
N
A
H
G
R
Rat
Rattus norvegicus
XP_573211
965
109012
S685
K
P
H
N
I
L
L
S
M
P
N
A
H
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
S658
K
P
H
N
I
L
I
S
M
P
N
A
H
G
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
S688
K
P
C
N
I
L
I
S
Y
P
S
A
H
G
K
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
S655
K
P
R
N
I
L
L
S
L
P
G
A
L
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
S676
K
P
Q
N
V
L
I
S
L
P
D
A
K
G
K
Honey Bee
Apis mellifera
XP_392044
968
110555
G663
L
C
K
K
L
Q
L
G
R
V
S
F
S
R
R
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
G669
L
C
K
R
V
Q
P
G
K
N
S
I
S
R
G
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
S715
K
P
H
N
V
L
I
S
Q
P
N
Q
H
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
R843
D
S
G
Q
S
S
F
R
T
N
L
N
N
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
0
100
86.6
N.A.
86.6
86.6
N.A.
93.3
N.A.
80
60
N.A.
66.6
0
0
80
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
N.A.
86.6
80
N.A.
86.6
26.6
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
65
0
0
0
% A
% Cys:
0
15
8
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
8
8
0
0
0
15
0
0
8
0
0
72
8
% G
% His:
0
0
50
0
0
0
0
0
0
0
0
0
58
0
0
% H
% Ile:
0
0
0
0
58
8
43
0
0
0
0
8
0
0
0
% I
% Lys:
72
0
15
8
0
0
0
0
8
0
0
0
8
0
36
% K
% Leu:
15
0
0
0
8
72
36
0
15
0
15
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
43
8
0
0
0
0
0
% M
% Asn:
0
0
0
72
0
0
0
0
0
15
50
8
8
0
0
% N
% Pro:
0
72
0
0
0
0
8
8
0
72
0
0
0
8
0
% P
% Gln:
0
0
8
8
0
15
0
0
8
0
0
8
0
0
8
% Q
% Arg:
0
0
8
8
0
0
0
8
8
0
0
0
0
15
36
% R
% Ser:
0
8
0
0
8
8
0
72
0
0
22
8
15
0
8
% S
% Thr:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
22
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _