KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
34.55
Human Site:
T891
Identified Species:
58.46
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
T891
T
D
L
R
K
F
R
T
Y
K
G
G
S
V
R
Chimpanzee
Pan troglodytes
XP_511585
968
108684
T882
A
Y
L
R
K
F
R
T
Y
K
G
G
S
V
R
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
T984
T
D
L
R
K
F
R
T
Y
K
G
G
S
V
R
Dog
Lupus familis
XP_853409
975
109686
T889
T
D
L
R
K
F
R
T
Y
K
G
G
S
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
T891
T
D
L
R
K
F
R
T
Y
K
G
G
S
V
R
Rat
Rattus norvegicus
XP_573211
965
109012
T879
T
D
L
R
K
F
R
T
Y
K
G
G
S
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
T852
T
D
L
R
K
F
R
T
Y
K
G
G
S
V
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
P872
W
R
L
H
I
S
V
P
L
Q
T
D
L
R
K
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
N831
G
R
S
V
V
R
T
N
W
R
M
H
I
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
G871
D
D
L
R
K
Y
R
G
Y
M
G
A
S
V
R
Honey Bee
Apis mellifera
XP_392044
968
110555
S832
T
D
L
R
K
Y
R
S
Y
R
G
E
S
V
R
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
T837
E
D
L
R
K
F
R
T
Y
K
S
F
S
V
R
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
A907
T
D
L
R
K
F
R
A
Y
R
G
H
S
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
K1028
P
S
G
D
W
T
V
K
F
D
K
T
F
M
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
86.6
100
100
N.A.
100
100
N.A.
100
N.A.
6.6
0
N.A.
66.6
73.3
80
80
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
100
N.A.
20
13.3
N.A.
73.3
93.3
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
72
0
8
0
0
0
0
0
8
0
8
0
0
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
65
0
0
8
0
0
8
8
0
0
% F
% Gly:
8
0
8
0
0
0
0
8
0
0
72
50
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
15
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
79
0
0
8
0
58
8
0
0
0
8
% K
% Leu:
0
0
86
0
0
0
0
0
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
15
0
79
0
8
79
0
0
22
0
0
0
8
79
% R
% Ser:
0
8
8
0
0
8
0
8
0
0
8
0
79
8
0
% S
% Thr:
58
0
0
0
0
8
8
58
0
0
8
8
0
0
0
% T
% Val:
0
0
0
8
8
0
15
0
0
0
0
0
0
79
0
% V
% Trp:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
15
0
0
79
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _