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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
13.94
Human Site:
Y179
Identified Species:
23.59
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
Y179
E
L
R
W
N
A
T
Y
F
D
Y
A
A
S
L
Chimpanzee
Pan troglodytes
XP_511585
968
108684
L176
V
G
K
Y
S
T
S
L
Y
A
S
P
S
M
V
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
Y272
E
L
R
W
N
A
T
Y
F
D
Y
A
A
S
L
Dog
Lupus familis
XP_853409
975
109686
Y179
E
L
R
W
N
A
T
Y
F
D
Y
A
A
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
Y181
E
L
R
W
N
A
T
Y
F
D
Y
A
A
S
L
Rat
Rattus norvegicus
XP_573211
965
109012
D179
Y
A
A
S
L
P
E
D
D
V
D
Y
K
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
V177
G
D
G
L
V
V
T
V
D
S
E
S
G
D
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
F184
E
L
R
W
N
A
T
F
H
D
Y
S
A
P
M
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
Y177
W
N
A
T
Y
N
D
Y
S
A
P
L
Y
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
G178
G
K
E
G
E
Q
I
G
W
A
T
S
R
A
I
Honey Bee
Apis mellifera
XP_392044
968
110555
M177
K
N
T
C
P
V
E
M
Q
N
A
V
F
M
G
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
F191
G
K
T
W
N
A
T
F
N
D
Y
S
A
H
L
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
V201
N
S
N
K
I
W
N
V
T
F
A
D
Y
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
I179
E
P
F
G
D
G
N
I
Y
Y
F
N
A
H
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
6.6
N.A.
66.6
6.6
N.A.
0
0
53.3
6.6
P-Site Similarity:
100
46.6
100
100
N.A.
100
0
N.A.
20
N.A.
86.6
6.6
N.A.
26.6
13.3
66.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
0
43
0
0
0
22
15
29
50
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
8
8
15
43
8
8
0
15
8
% D
% Glu:
43
0
8
0
8
0
15
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
15
29
8
8
0
8
0
0
% F
% Gly:
22
8
8
15
0
8
0
8
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
15
0
% H
% Ile:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
8
% I
% Lys:
8
15
8
8
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
36
0
8
8
0
0
8
0
0
0
8
0
0
36
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
22
8
% M
% Asn:
8
15
8
0
43
8
15
0
8
8
0
8
0
0
0
% N
% Pro:
0
8
0
0
8
8
0
0
0
0
8
8
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
36
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
8
8
0
8
0
8
8
8
29
8
36
15
% S
% Thr:
0
0
15
8
0
8
50
0
8
0
8
0
0
0
0
% T
% Val:
8
0
0
0
8
15
0
15
0
8
0
8
0
0
15
% V
% Trp:
8
0
0
43
0
8
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
0
0
36
15
8
43
8
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _